Results 61 to 70 of about 25,200 (252)

Laser treatment of drusen to prevent progression to advanced age-related macular degeneration. [PDF]

, 2009
BACKGROUND: Drusen are amorphous yellowish deposits beneath the sensory retina. People with drusen, particularly large drusen, are at higher risk of developing age-related macular degeneration (AMD).
Abdelsalam, Alexander, Anonymous, Anonymous, Bressler, Bressler, Bressler, Brown, Chakravarthy, Chong, Cleasby, Duvall, Elbourne, Evans, Figueroa, Figueroa, Figueroa, Figueroa, Fine, Frennesson, Frennesson, Frennesson, Frennesson, Frennesson, Friberg, Gass, Glanville, Gross-Jendroska, Grunwald, Guidry, Guymer, Hassell, Ho, Ho, Holz, Kaiser, Kertes, Klein, Little, Little, Maguire, Maguire, Mangione, Olk, Owen, Owens, Owens, Owens, Pauleikhoff, Pauleikhoff, Phipps, Prenner, Regillo, Rodanant, Rosenbaltt, Sarks, Sarraf, Sbarbaro, Sigelman, Sivagnanavel, Smith, Stoltz, Vingerling, Wetzig, White, Ying, Young   +66 more
core   +1 more source

Visual Function Assessment in Geographic Atrophy: A Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Geographic atrophy (GA) causes significant vision impairment and reduction in vision‐related quality of life. Fundus autofluorescence (FAF) is the gold standard of structural assessment of GA but is a surrogate marker for vision loss, which can be assessed by tests of visual function and functional vision.
Ye Li, Lauren N. Ayton, Adrian T. Fung
wiley   +1 more source

Intraocular Osseous Metaplasia in Norfolk Black Turkey (Meleagris gallopavo): Clinicopathological Characterization of a Rare Avian Condition

Veterinary Ophthalmology, EarlyView.
ABSTRACT Background Osseous metaplasia is a rare condition characterized by abnormal bone growth in soft tissues. Although documented in mammals, intraocular osseous metaplasia is uncommon in avian species and has been poorly characterized in turkeys (Meleagris gallopavo).
Taina dos Santos Alberti, Andressa Trindade Nogueira, Magale Dallaporta Furquim, Driele Fernanda dos Santos, Rosimeri Zamboni, Eliza Simone Viégas Sallis, Clairton Marcolongo‐Pereira   +6 more
wiley   +1 more source

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio, Reilly, James, Shu, Xinhua, Tiano, Luca, Tohari, Ali Mohammad, Zhang, Xun, Zhou, Xinzhi   +6 more
core   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

BioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra, Chia‐Che Ku, Ying‐Chu Lin, Yi‐Chun Tsai, Deng‐Chyang Wu, Yukio Mitsui, Maki Satou, Yuuki Tanaka, Shigeo Saito, Kazunari K. Yokoyama   +9 more
wiley   +1 more source

Automated detection of age-related macular degeneration in color fundus photography:a systematic review [PDF]

, 2019
The rising prevalence of age-related eye diseases, particularly age-related macular degeneration, places an ever-increasing burden on health care providers.
Cameron, James, Dhillon, Baljean, Fleming, Alan, MacGillivray, Thomas, Megaw, Roly, Pead, Emma, Trucco, Emanuele   +6 more
core   +4 more sources

The Use of Combined Fundus Photography and Perimetry for the Assessment of Patients Referred for Intracranial Hypertension or Follow‐Up of the Diagnosis in a Tertiary Headache Center

European Journal of Neurology, Volume 33, Issue 1, January 2026.
ABSTRACT Objectives Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure and papilledema. If left untreated, it can lead to vision loss, and, timely detection of papilledema is of paramount importance. Direct ophthalmoscopy can be difficult to perform and interpret for non‐ophthalmologists.
Zainab Rissan, Nadja Skadkær Hansen, Vlasta Vukovic‐Cvetkovic, Louise Ninett Carlsen, Steffen Hamann, Marianne Wegener, Rigmor H. Jensen, Henrik Winther Schytz   +7 more
wiley   +1 more source

Early Detection of Incipient Retinal Pigment Epithelium Atrophy Overlying Drusen with Fundus Autofluorescence vs. Spectral Domain Optical Coherence Tomography

Journal of Ophthalmology, 2020
Purpose. This study aims to find out which tool, fundus autofluorescence (FAF) or spectral domain optical coherence tomography (SD-OCT), is more sensitive in detecting retinal pigment epithelium (RPE) demise overlying drusen and can, therefore, help ...
Anabel Rodríguez, Marc Biarnés, Rosa M. Coco-Martin, Anna Sala-Puigdollers, Jordi Monés   +4 more
doaj   +1 more source

Drusen morphometrics on optical coherence tomography in eyes with age-related macular degeneration and normal aging [PDF]

, 2023
Deniz Oncel, Giulia Corradetti, Yu Wakatsuki, Muneeswar Gupta Nittala, Swetha Bindu Velaga, Dwight Stambolian, Margaret A. Pericak‐Vance, Jonathan L. Haines, Srinivas R. Sadda   +8 more
openalex   +1 more source

Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells [PDF]

, 2019
Age-related macular degeneration is the main cause of vision loss in the aged population worldwide. Drusen, extracellular lesions formed underneath the retinal pigment epithelial (RPE) cells, are a clinical feature of AMD and associated with AMD ...
Abdulwahab Alamri, David Watson, Farooqui, Lincoln Biswas, Rohrer, Suzuki, Winkler, Xinhua Shu   +7 more
core   +2 more sources