Results 61 to 70 of about 31,224 (320)

Ex Vivo Hyperspectral Autofluorescence Imaging and Localization of Fluorophores in Human Eyes with Age-Related Macular Degeneration

open access: yesVision, 2018
To characterize fluorophore signals from drusen and retinal pigment epithelium (RPE) and their changes in age related macular degeneration (AMD), the authors describe advances in ex vivo hyperspectral autofluorescence (AF) imaging of human eye tissue ...
Taariq Mohammed   +9 more
doaj   +1 more source

3D Structural Analysis of the Optic Nerve Head to Robustly Discriminate Between Papilledema and Optic Disc Drusen [PDF]

open access: yesarXiv, 2021
Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy, optic disc drusen (ODD), and papilledema ONHs.
arxiv  

Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study.

open access: yesJournal of neuro-ophthalmology, 2020
BACKGROUND The purpose of the study was to examine 5-year changes in eyes with optic disc drusen at baseline on optical coherence tomography (OCT) scans and the relation of incident drusen to hyperreflective prelaminar lines. METHODS The study included
L. Malmqvist   +8 more
semanticscholar   +1 more source

Complement C3 variant and the risk of age-related macular degeneration [PDF]

open access: yes, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM   +16 more
core   +1 more source

Automatic Drusen Segmentation for Age-Related Macular Degeneration in Fundus Images Using Deep Learning

open access: yesElectronics, 2020
Drusen are the main aspect of detecting age-related macular degeneration (AMD). Ophthalmologists can evaluate the condition of AMD based on drusen in fundus images. However, in the early stage of AMD, the drusen areas are usually small and vague.
Quang T. M. Pham   +3 more
semanticscholar   +1 more source

Population-Based Prevalence and 5-Year Change of Soft Drusen, Pseudodrusen, and Pachydrusen in a Japanese Population

open access: yesOphthalmology Science, 2021
Purpose: To elucidate the prevalence of soft drusen, pseudodrusen, and pachydrusen and their 5-year changes in a Japanese population. Design: Longitudinal population-based cohort study conducted from 2013 through 2017. Participants: Residents 40 years of
Miki Sato-Akushichi, MD   +7 more
doaj  

Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells [PDF]

open access: yes, 2019
Age-related macular degeneration is the main cause of vision loss in the aged population worldwide. Drusen, extracellular lesions formed underneath the retinal pigment epithelial (RPE) cells, are a clinical feature of AMD and associated with AMD ...
Abdulwahab Alamri   +7 more
core   +2 more sources

Antecedents of Soft Drusen, the Specific Deposits of Age-Related Macular Degeneration, in the Biology of Human Macula

open access: yesInvestigative Ophthalmology and Visual Science, 2018
AMD pathobiology was irreversibly changed by the recent discovery of extracellular cholesterol-containing deposits in the subretinal space, between the photoreceptors and retinal pigment epithelium (RPE), called subretinal drusenoid deposits (SDDs). SDDs
C. Curcio
semanticscholar   +1 more source

Long-term Evolution and Remodeling of Soft Drusen in Rhesus Macaques

open access: yesInvestigative Ophthalmology and Visual Science, 2020
Purpose To characterize the evolution and structure of soft drusen in aged rhesus macaques using in vivo multimodal retinal imaging and ex vivo histologic and ultrastructural analyses as a nonhuman primate model of early age-related macular degeneration (
Glenn Yiu   +9 more
semanticscholar   +1 more source

Drusen Segmentation From Retinal Images via Supervised Feature Learning

open access: yesIEEE Access, 2018
This paper presents a supervised feature learning method to learn discriminative and compact descriptors for drusen segmentation from retinal images.
Xiuxiu Ren   +6 more
doaj   +1 more source

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