Results 71 to 80 of about 1,948,356 (316)

Effect of MQL on wear behavior of various coated tools in hobbing (Fundamental experiments using fully coated tools)

open access: yesNihon Kikai Gakkai ronbunshu, 2014
This paper deals with the effect of minimal quantity lubrication (MQL) on tool life (flank wear), crater wear of various coated high-speed steel tools and finished surface roughness in hobbing. Experiments were conducted by simulation hobbing by fly tool
Hironori MATSUOKA   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Similarity solutions for unsteady shear-stress-driven flow of Newtonian and power-law fluids : slender rivulets and dry patches

open access: yes, 2011
Unsteady flow of a thin film of a Newtonian fluid or a non-Newtonian power-law fluid with power-law index N driven by a constant shear stress applied at the free surface, on a plane inclined at an angle α to the horizontal, is considered.
Wilson, Stephen   +5 more
core   +1 more source

An experimental investigation on the airside performance of fin-and-tube heat exchangers having corrugated louver fins - Part I; dry surface

open access: yesJournal of Thermal Science and Technology, 2020
Corrugated louver fin, which has louvers on wavy surface, may be a promising mean to augment the air-side heat transfer of fin-and-tube heat exchangers. However, only limited prior studies are available.
Nae-Hyun KIM
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Travelling-wave similarity solutions for an unsteady shear-stress-driven dry patch in a flowing film

open access: yes, 2013
We investigate unsteady flow of a thin film of Newtonian fluid around a symmetric slender dry patch moving with constant velocity on an inclined planar substrate, the flow being driven by a prescribed constant shear stress at the free surface of the film
Duffy, B.R.   +2 more
core  

Environmental changes during secondary succession in a tropical dry forest in Mexico

open access: yes, 2011
Vegetation and environment change mutually during secondary succession, yet the idiosyncrasies of the vegetation effect on the understorey environment are poorly understood. To test whether the successional understorey environment changes predictably and
Lebrija Trejos, E.E.   +4 more
core   +1 more source

Drying of Filament in Dry Spinning

open access: yesChemical engineering, 1966
1963年に“物性定数1集”が発行されてもう3年目となる。そもそも化学工学の研究者や化学工業の技術者にとって, 物性定数とは不可分の関係にあり, 化学工学実験を整理して式を導く場合やまたは既存の式により設計計算をする場合に必要欠くべからざる要素である。しかるにこの物性定数の測定及び整理については, 一般の化学工学実験を行なうセンスでは到底精度が得られず, 精密分析や精密工業のような非常に緻密なセンスが必要で, 従来は化学工学屋にとって苦手な所であった。しかし化学工業の発展に伴い, 我々の取扱わねばならぬ物質も増加し, 又化学工業の技術の進歩により, その温度, 圧力, 混合状態等の範囲は拡大の一歩をたどっている。一方化学工学の進化に伴い, 新しい物性定数の要求がある ...
Sano, Yuzi, Nishikawa, Shinzo
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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