Results 141 to 150 of about 17,907 (178)
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Association of NLRPs with pathogenesis of dry age-related macular degeneration
International Ophthalmology, 2023Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and Dry AMD is the most common clinical subtype. However, effective measures for the early diagnosis and treatment of dry AMD have not been proposed. In recent years, NOD-like receptors (NLRs) have received attention in the study of AMD as an important ...
Yiyun, Zeng +3 more
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Inflammation in Dry Age-Related Macular Degeneration
Ophthalmologica, 2007<i>Purpose:</i> To summarize the current information regarding the role of immune and inflammatory response in the pathogenesis of dry age-related macular degeneration (ARMD). <i>Methods:</i> A Pubmed search was conducted of the period January 1999 to 2005.
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Treatment of nonexudative (dry) age-related macular degeneration
Current Opinion in Ophthalmology, 2006The purpose of this report is to review the recent literature and summarize currently available and potential new treatment options for nonexudative age-related macular degeneration.High-dose vitamin supplementation may have some associated systemic toxicity. It is important to check that the patient is taking beta-carotene and not vitamin A as retinal
Mark J, Donaldson, Jose S, Pulido
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Influence of vitrectomy on the progression of dry age-related macular degeneration
Graefe's Archive for Clinical and Experimental Ophthalmology, 2020To demonstrate whether pars plana vitrectomy (PPV) changes the progression of dry age-related macular degeneration (AMD) by assessing longitudinal changes in drusen volume over follow-up.Dry AMD patients who had undergone unilateral PPV for symptomatic vitreomacular disorders were evaluated for the progression of disease by spectral domain-optical ...
Ilkay Kilic, Muftuoglu +3 more
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HTRA1 POLYMORPHISM IN DRY AND WET AGE-RELATED MACULAR DEGENERATION
Retina, 2008To investigate HTRA1 polymorphisms in unrelated Taiwan Chinese patients with age-related macular degeneration (AMD) and control subjects without AMD.A total of 95 unrelated Taiwan Chinese patients with AMD and 90 age- and sex-matched control subjects were enrolled in the study.
Jane-Ming, Lin +8 more
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Challenges in the Development of Therapy for Dry Age-Related Macular Degeneration
2015Dry age-related macular degeneration (AMD), a multifactorial progressive degenerative disease of the retinal photoreceptors, pigmented epithelium and Bruch's membrane/choroid in central retina, causes visual impairment in millions of elderly people worldwide.
Cynthia X, Wei +7 more
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Complement therapy in dry age-related macular degeneration
Drug Discovery Today: Therapeutic Strategies, 2013The leading cause of vision loss in industrialized countries is age-related macular degeneration (AMD) and its prevalence is increasing with the ageing of the population. Thus, since dysfunction of the local complement system is associated with AMD, the retinal pigment epithelium–choroid complex is a potential location for the delivery of novel ...
Omar S. Punjabi, Peter K. Kaiser
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Retinal neuroprotection in dry age-related macular degeneration
Drug Discovery Today: Therapeutic Strategies, 2013Dry age-related macular degeneration (AMD) is a slowly progressive visual disorder that is a leading cause for severe visual impairment in the elderly population. Clinical options to prevent disease development and progression are very limited at this time.
Nicholas D. Chinskey +2 more
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Global Burden of Dry Age-Related Macular Degeneration: A Targeted Literature Review
Clinical Therapeutics, 2021Neil M Schultz +2 more
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