Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Analysis of spectral response patterns of Kiwifruit orchards using satellite imagery to predict orchard characteristics of commercial value before harvest : : a thesis presented in fulfilment of the requirements for the degree of PhD Prod Tech in the School of Engineering and Advanced Technology at Massey University, Palmerston North, New Zealand [PDF]
Several characteristics of kiwifruit determine its value to the kiwifruit marketing company, Zespri Ltd, and to the grower. The foremost of these is the dry matter content.
Mills, Linda Yvonne
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Dry matter losses can be a remarkable cost factor and emission source in biomass supply for energy and biorefining. Roundwood is not sensitive for dry matter losses and that is why storing along a supply chain and in terminals should be focused on roundwood, if possible.
Raitila, Jyrki, Sikanen, Lauri
+6 more sources
Efficient use of nitrogen for medicinal plants production, might increase flower dry matter, essential oil and extract yield and reduce cost of yield production.
ali akbar ameri +2 more
doaj +1 more source
Determination of chemical properties in ‘calçot’ (Allium cepa L.) by near infrared spectroscopy and multivariate calibration [PDF]
‘Calçots’, the immature floral stems of second-year onion resprouts, are an economically important traditional crop in Catalonia (Spain). Classical approaches to evaluating the chemical properties of ‘calçots’ are time consuming and expensive; near ...
Boqué, Ricard +5 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Effect of Variety, Sowing Date and Location on Yield and Nutritional Characteristics of Sorghum
Sorghum is a forage species important in animal nutrition with an increased potential in the upcoming difficulties in agricultural practices in regard to climate change.
Ivana Koláčková +7 more
doaj +1 more source
【Objective】 The purpose of this paper is to investigate the effect of drip irrigation amount on dry matter accumulation and distribution, as well as the yield formation of the grain machine harvest maize.
SHI Jingjing +9 more
doaj +1 more source
Effects of forage supplements on milk production and chemical properties, in vivo digestibility, rumen fermentation and N excretion in dairy cows offered red clover silage and corn silage or dry ground corn [PDF]
peer-reviewedThis study concerned the effects of partial substitution of clover silage with high starch forages on milk production and chemical composition, in vivo digestibility, rumen fermentation pattern and nitrogen excretion of dairy cows.
Arriaga, H. +3 more
core

