Results 61 to 70 of about 32,227 (313)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

TRIBOELECTRIFICATION OF SHOE COVER AND FLOOR IN HOSPITALS [PDF]

Journal of the Egyptian Society of Tribology, 2015
Electric static charges generated from friction of engineering materials have a negative effect on their applications. The increased use of polymeric materials raised the importance of studying that effect.
A. S. Ali, W. Y. Ali, Y. M. El-Sherbiny
doaj   +1 more source

Sliding wear of nitrided steels [PDF]

, 1993
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The unlubricated sliding wear behaviour of gas nitrided, plasma nitrided, and ferritic nitrocarburized BS970,905M39 (EN41B) steels was investigated ...
Kato, Hirotaka, Kato, H
core  

Bifurcations of piecewise smooth flows:perspectives, methodologies and open problems [PDF]

, 2012
In this paper the theory of bifurcations in piecewise smooth flows is critically surveyed. The focus is on results that hold in arbitrarily (but finitely) many dimensions, highlighting significant areas where a detailed understanding is presently lacking ...
A. Colombo, M. R. Jeffrey, DI BERNARDO, MARIO, S. J. Hogan, Hogan, S. J., M. di Bernardo, Colombo, Alessandro, Jeffrey, MR, S.J. Hogan, M.R. Jeffrey, di Bernardo, M   +10 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Analysis of wear mechanism in TPU-steel contact pair by means of long stroke tribometer tests [PDF]

, 2012
A complete wear characterisation of a thermoplastic polyurethane (TPU) sliding against steel is presented. Wear tests were performed using a long stroke tribometer under sliding reciprocating movement and dry conditions.
Jiménez, Miguel Angel, Delbé, Karl, Yahiaoui, Malik, Paris, Jean-Yves, Canales, Margarita, Martinez, Francisco Javier, Alcalà, Noelia, Ural, Aydemir Güralp, Denape, Jean   +8 more
core  

Fe nano-particle coatings for high temperature wear resistance [PDF]

, 2011
Oxidational wear continues to present an economic challenge for the replacement of components subject to high temperature fretting and sliding contacts in applications such as gas turbine engines.
S.R. Saranu, A.H. Kean, Wood, R.J.K., Robert Wood, Walker, J.C., John Christopher Walker, A. H. Kean, Saranu, S.R., J.C. Walker, S. R. Saranu, R. J. K. Wood, Kean, A.H., R.J.K. Wood   +12 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Microstructural evolution and enhanced tribological performance of multi-component Al–Fe–Mn–Cu Alloys: A comparative study between conventional casting and laser powder bed fusion

Journal of Materials Research and Technology
This study investigates the influence of microstructural architecture on the tribological performance of multi-component Al–Fe–Mn–Cu alloys fabricated via conventional casting and Laser powder bed fusion (LPBF).
Seungon Lim, Dasom Kim, Naoki Takata, Se-Eun Shin   +3 more
doaj   +1 more source