Results 51 to 60 of about 3,169,044 (403)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Multifilm Mass Transfer and Reaction Rate Kinetics in a Newly Developed In Vitro Digestion System for Carbohydrate Digestion

Foods
Multifilm mass transfer theory has been used in conjunction with developing a new in vitro starch digestion model and applied to assessing starch digestion kinetics. One significance of this research is that this in vitro model has similar dynamics, such
Yongmei Sun, Jingying Cheng, Shu Cheng, Timothy A. G. Langrish   +3 more
doaj   +1 more source

Material hold-up on inert particles in fluidized bed dryer [PDF]

Hemijska Industrija
In this paper the influence of process parameters on the material hold-up in a fluidized bed dryer with inert particles was investigated. The experiments were performed in a pilot-scale dryer with a cylindrical column 0.215 m in diameter and 1.2 m height,
Đuriš Mihal M., Arsenijević Zorana LJ., Kaluđerović-Radoičić Tatjana S.   +2 more
doaj   +1 more source

Recovering superhydrophobicity in nanoscale and macroscale surface textures [PDF]

, 2019
Here, we investigate complete drying of hydrophobic cavities in order to elucidate its dependence on the size of confinement, its geometry, and the degree of hydrophobicity. Two complementary theoretical approaches are adopted: a macroscopic one based on
Dietrich, Siegfried, Giacomello, Alberto, Schimmele, Lothar, Tasinkevych, Mykola   +3 more
core   +1 more source

Spray Drying for the Preparation of Nanoparticle-Based Drug Formulations as Dry Powders for Inhalation

Processes, 2020
Nanoparticle-based therapeutics have been used in pulmonary formulations to enhance delivery of poorly water-soluble drugs, protect drugs against degradation and achieve modified release and drug targeting.
M. Malamatari, Anastasia Charisi, S. Malamataris, K. Kachrimanis, I. Nikolakakis   +4 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

PHYSIOLOGICAL QUALITY OF CHICKPEA (CICER ARIETINUM L.) SEEDS UNDER STORAGE AND ENVIRONMENTAL VARIATIONS [PDF]

Engenharia Agrícola
Chickpea has recently gained prominence in agriculture, being an excellent option for crop rotation in areas cultivated with soybean or corn. Seeds must have good physiological quality, mainly during storage, to ensure crop success.
Marcos D. R. de Oliveira, Karine Von Ahn Pinto, Graciela Buck, Amanda M. Silva, Gizele I. Gadotti   +4 more
doaj   +1 more source

Drying apparatus for photographic sheet material [PDF]

, 1973
An elongated drying chamber is provided with transport means for carrying photographic sheet material edgewise with the sheets in end-to-end relationship past a plurality of tubes that issue drying air streams.
Donovan, G., Epstein, P., Lawhite, E.
core   +1 more source

Metallic salt deposition on porous particles by dry impregnation in fluidized bed: Effect of drying conditions on metallic nanoparticles distribution [PDF]

, 2009
In this paper, the fluidized bed dry impregnation of coarse alumina porous particles by a metallic salt, manganese nitrate, is investigated. In this technique the penetration of each drop of metallic solution in the porous solid particle and solvent ...
Barthe, Laurie, Desportes, Serge, Hemati, Mehrdji, Steinmetz, Daniel   +3 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source