Results 61 to 70 of about 4,478,688 (304)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Low temperature dry cells

Journal of the Franklin Institute, 1946
Two types of dry cells have been produced to give acceptable electric output at temperatures of −30° C and lower. One involves an electrolyte comprising an aqueous solution of methylamine hydrochloride and zinc chloride with added ammonium chloride, while the other uses an electrolyte consisting of an aqueous solution of calcium chloride and zinc ...
Earl Otto, C. K. Morehouse, George W. Vinal   +2 more
openaire   +2 more sources

Effect of Operating Temperature and Humidity in Heat Pump Drying on Energy Consumption and Drying Characteristics of Apple Slices

Agriculture
In the current work, a novel heat pump drying system with precise control of temperature and humidity of drying medium was developed and the impacts of drying temperature and humidity on the drying characteristics of apple slices and energy consumption ...
Xianlong Yu, Bin Chu, Zhenchao Jia, Suchao Ma, Wenxuan Wu, Ziliang Liu, Ligang Sun   +6 more
doaj   +1 more source

Improving the Efficiency of Seed Drying in a Reversible Grain Dryer

Сельскохозяйственные машины и технологии, 2023
Reverse drying is acknowledged to be widely used in the woodworking industry, and in corn cob drying, but it is hardly used for drying grass and cereal seeds. It can be explained by insufficient research into the matter.
M. G. Zagoruyko, S. A. Pavlov, I. A. Bashmakov   +2 more
doaj   +1 more source

Development of model based sensors for the supervision of a solar dryer [PDF]

, 2011
Solar dryers are increasingly used in developing countries as an alternative to drying in open air, however the inherent variability of the drying conditions during day and along year drive the need for achieving low cost sensors that would enable to ...
Correa Hernando, Eva Cristina, Diezma Iglesias, Belen, Juliá, Eduardo, Arranz Saiz, Francisco Javier, García-Hierro, Javier, Robla Villalba, José Ignacio, Ruiz García, Luis, Barreiro Elorza, Pilar, Juliá, E., B. Diezma, P. Barreiro, Arranz, F. J., Correa-Hernando, E., Robla, J. I., F.J. Arranz, L. Ruiz-Garcia, García-Hierro, J., J.I. Robla, J. García-Hierro, Diezma, Belén, E. Juliá, Barreiro, Pilar, Ruiz-García, L., E. Correa-Hernando   +23 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Drying Spirulina with Foam Mat Drying at Medium Temperature

International Journal of Science and Engineering, 2012
Spirulina is a single cell blue green microalgae (Cyanobacteria) containing many Phytonutrients (Beta-carotene, Chlorophyl, Xanthophyl, Phyocianin) using as anti-carcinogen in food. Producing dry spirulina by quick drying process at medium temperature is very important to retain the Phytonutrient quality. Currently, the work is still challenging due to
Aji , Prasetyaningrum, Mohamad , Djaeni
openaire   +3 more sources

Shrinkage of recycled paper sheet during drying

, 2015
The properties of recycled paper are strongly affected by shrinking during drying, which depends on the drying conditions. An experimental study of the shrinkage phenomenon during drying of paper is presented.
Rocha, SCS, Estrella, L, Silva, MA, Vieira, MGA   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Influence of temperature on ‘Rojo Brillante’ persimmon drying. Quality characteristics and drying kinetics

LWT, 2023
[EN] A physico-chemical characterization and drying kinetics study was performed for whole `Rojo Brillante¿ persimmon subjected to hot-air drying at 35 ¿C, 40 ¿C and 45 ¿C. Fruit was dried until a moisture content of 30 g water/100 g product, which is required to be considered dried persimmon.
Cervera-Chiner, Lourdes, Larrea Santos, Virginia, Moraga Ballesteros, Gemma, Vilhena, Nariane Q., Salvador Pérez, Alejandra   +4 more
openaire   +3 more sources