Results 51 to 60 of about 343,483 (267)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Influence of air flow rate on drying characteristics of clove [PDF]
, 2013 Clove is one of the major state crops in South Sulawesi, Indonesia. In 2011 total planted area in this region reached about 44,000 hectares. Although drying is a crucial step, information concerning the drying behaviors of clove is limited. This research
Junaedi
core
Temperature controlled infrared drying kinetics of mussels
, 2019 Department of Chemical Engineering, Yildiz Technical University, Esenler, Istanbul, Turkey E-mail: skipcak@yildiz.edu.tr Manuscript received online 26 April 2019, revised and accepted 20 July 2019 Mussel has impressive nutritional values, which contains many vitamins, minerals and proteins by comparison with other shellfish.
Kıpçak, Azmi Seyhun +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
High temperature drying of sawn timber—A review [PDF]
Sawn-timber drying is the wood industry’s most time- and energy-consuming process. This process can be more efficient than the conventional method by elevating the dry-bulb temperature to above 100 °C in a high-temperature drying (HTD) process, which for
Hansson, Lars, +7 more
core +1 more source
Estimation of friction surface temperature of a dry clutch
International Journal of Heavy Vehicle Systems, 2020 This paper presents an approach to estimate the temperature on the friction surface of a dry clutch. The study comprises both experimental measurements and transient thermal numerical analysis of heavy duty truck clutches for the successive engagements on a slope road.
Cakmak, Tolga, Kilic, Muhsin
openaire +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Comparison on Modelling of Drying Kinetics of Granular Polymers PA6 by Diffusion Models and Normalization Method [PDF]
, 2012 In this work, the drying behaviour of single granular PA6, hanging in the flow direction of hot air in a drying chamber, was investigated. In the experiments, the air was passed through the chamber at contant very low velocity in the drying chamber of ...
S, Suherman +2 more
core
A model for through-drying of tissue paper at constant pressure drop and high drying intensity [PDF]
, 2007 A mathematical model for through drying of paper at constant pressure drop was developed. The model is based on physical properties; hence, basis weight, pressure drop, drying air temperature, pore size distribution, initial gas fraction, and tortuosity ...
Stenström, Stig, +2 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source