Results 81 to 90 of about 1,362 (166)

Increased glymphatic system activity and thalamic vulnerability in drug-naive somatic depression: Evidenced by DTI-ALPS index

NeuroImage: Clinical
Major depressive disorder (MDD) is a significant contributor to global disease burden, with somatic symptoms frequently complicating its diagnosis and treatment.
Zipeng Deng, Wei Wang, Zhaowen Nie, Simeng Ma, Enqi Zhou, Xinhui Xie, Qian Gong, Lihua Yao, Lihong Bu, Lijun Kang, Zhongchun Liu   +10 more
doaj   +1 more source

Glymphatic System Dysfunction in Congenital Sensorineural Hearing Loss: A DTI-ALPS Study

Current Medical Imaging Formerly Current Medical Imaging Reviews
Background: The neural mechanisms underlying congenital sensorineural hearing loss (CSNHL) remain elusive. Objective: This study evaluated the function of the glymphatic system in children with CSNHL compared to normal-hearing children using the DTI-ALPS approach, which utilizes diffusion tensor imaging along the perivascular space.
Li, Sha, Zhen-Gui, Xu, Yu-Chen, Chen
openaire   +2 more sources

Assessing of the glymphatic system using DTI‐ALPS MRI in patients with neurodegenerative diseases

Alzheimer's & Dementia
AbstractBackgroundDysfunction of the glymphatic system (GS), a recently discovered brain by‐product elimination system, is considered to be one of the pathophysiological mechanisms for common neurodegenerative diseases such as Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and Parkinson's disease (PD).
Liaskovik, Alina, Fedotova, Ekaterina, Konovalov, Rodion, Krotenkova, Marina V., Shpilyukova, Yuliya, Nevzorova, Kseniya, Brsikyan, Lusine   +6 more
openaire   +1 more source

近期皮质下小梗死患者白质高信号与脑类淋巴系统功能的相关性研究Correlation between White Matter Hyperintensities and Glymphatic System Function in Patients with Recent Small Subcortical Infarcts

Zhongguo cuzhong zazhi
目的 探讨近期皮质下小梗死（recent small subcortical infarct，RSSI）患者不同部位、不同严重程度白质高信号（white matter hyperintensity，WMH）与脑类淋巴系统（glymphatic system，GS）功能的相关性。 方法 回顾性连续纳入南京医科大学第三附属医院（常州市第二人民医院）2023年12月—2024年12月收治的RSSI患者，其均于入院后3 d内完善头颅MRI检查（包含弥散张量成像序列）。利用沿血管周围间隙弥散张量成像分析 ...
张雪，张敏，吴鹏，恽文伟ZHANG Xue, ZHANG Min, WU Peng, YUN Wenwei
doaj   +1 more source

Diffusion tensor imaging along the perivascular space and choroid plexus volume for assessing the brain glymphatic system in overt hypothyroidism

Frontiers in Neurology
IntroductionThe neurocognitive impairment in overt hypothyroidism (OH) is well-recognized, but its underlying mechanisms remain unclear. The glymphatic system, a recently discovered brain waste-clearance pathway, represents a promising yet unexplored ...
Hong Yu, Yuting Wang, Feifei Zheng, Hailin Shao, Qing He, Xuehuan Liu, Hao Wang, Xiao Gao, Zuoxi Li, Jun Liu, Jun Liu   +10 more
doaj   +1 more source

Glymphatic dysfunction links vascular pathology to Alzheimer’s biomarkers and cognitive decline

Alzheimer’s Research & Therapy
Background Vascular damage, including cerebral amyloid angiopathy (CAA) and non-amyloid cerebral small vessel disease (CSVD), has been linked to glymphatic dysfunction, which may contribute to Alzheimer’s disease (AD) pathology and cognitive decline.
Sung Hoon Kang, Seongmi Kim, Young Ju Kim, Heejin Yoo, Eun Hye Lee, Hyemin Jang, Daeun Shin, Jihwan Yun, Jun Pyo Kim, Hee Jin Kim, Duk L. Na, Henrick Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Theresa A. Day, Marco Duering, Seong-Beom Koh, Sang-Young Kim, Eung Yeop Kim, Sung Tae Kim, Beomseok Sohn, Sang Won Seo   +22 more
doaj   +1 more source

Impairment of the intracranial lymphatic system in Parkinson’s disease: a combined study of the meningeal lymphatics vessels and glymphatic system based on noninvasive neuroimaging

European Journal of Medical Research
Background The role of intracranial lymphatic circulation in Parkinson’s disease (PD) causes more and more concerns nowadays. The drainage function of meningeal lymphatic vessels (MLVs) and the clearance capability of the glymphatic system have been ...
Mingxian Huang, Pan Zhang, Zhen Chen, Xiaoyang Wang, Hui Li, Shangwen Xu, Limin Lan, Wenxi Zheng, Hui Xiao   +8 more
doaj   +1 more source

Reassessment of the DTI-ALPS index in focal epilepsy. [PDF]

Eur Radiol Exp
Chambers S, Hofer L, Tranfa M, Kienast P, Shawarba J, Stepponat R, Jud J, Aull-Watschinger S, Pataraia E, Fischmeister FPS, Barkhof F, Hangel G, Rössler K, Pontillo G, Kasprian G, Haider L.   +15 more
europepmc   +1 more source

Anatomical determinants of DTI-ALPS: Effects of ROI definition, ventricular morphology, and periventricular deformation. [PDF]

Imaging Neurosci (Camb)
Wright DK.
europepmc   +1 more source

Choroid plexus enlargement is negatively associated with cognitive performance in a DTI-ALPS-dependent manner. [PDF]

Front Aging Neurosci
Tan NIYZ, Welton T, Tan YJ, Saffari SE, Morgenroth E, Foo SJY, Kwok ZR, Lim YC, Chiew HJ, Ng KP, Ting SKS, Kumar S, Keong N, Ng ASL.   +13 more
europepmc   +1 more source