Results 61 to 70 of about 194,537 (375)

Relationship Between DTI Metrics and Cognitive Function in Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2019
Introduction: Alzheimer’s disease (AD) is a neurodegenerative disorder with a clinical presentation characterized by memory impairment and executive dysfunction.
Chantel D. Mayo, M. Garcia-Barrera, E. Mazerolle, L. Ritchie, J. Fisk, Jodie R. Gawryluk   +5 more
semanticscholar   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Prediction of Longitudinal White Matter Change in Healthy Elderly Individuals [PDF]

, 2012
Diffusion Tensor Imaging (DTI) studies have shown that significant alteration in white matter (WM) integrity differentiates healthy older adults from persons with Mild Cognitive Impairment (MCI) and Alzheimer\u27s disease (AD).
Butts, Alissa, Durgerian, Sally, Hantke, Nathan, Lancaster, Melissa A., Matthews, Monica, Nielson, Kristy A., Rao, Stephen M., Seidenberg, Michael, Smith, J. Carson, Woodard, John L.   +9 more
core   +1 more source

White matter changes and confrontation naming in retired aging national football league athletes [PDF]

, 2017
Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group.
Bartz, Elizabeth K, Conover, Heather, Cullum, C. Munro, Didehbani, Nyaz, Fields, Lindy M, Hart, John, Jr, Jeroudi, Myrtle K, Kraut, Michael A, Mansinghani, Sethesh, Rao, Neena K, Spence, Jeffrey, Strain, Jeremy F, Womack, Kyle B   +12 more
core   +2 more sources

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Characteristics of the White Matter Structural Network in Individuals with Subjective Cognitive Decline with and without APOEε4 Based on Graph Theory Study

Journal of Integrative Neuroscience
Purpose: To determine whether individuals with subjective cognitive decline (SCD) have changes in whole-brain network characteristics and intracerebral node characteristics in the structural network, and whether there is a difference between SCD with and
Simin Deng, Weijie Chen, Suibin Feng, Huote Lai, Wei Lai   +4 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Level of CSF GAP-43 and white matter microstructural changes in Alzheimer's disease [PDF]

Neurology Letters
Objectives: Several studies have reported altered cerebrospinal fluid (CSF) concentrations of presynaptic proteins, such as growth-associated protein 43 (GAP-43) in Alzheimer's disease (AD)  patients. Given the potential predictive role of CSF GAP-43 for
Marjan Assefi, Alireza Sharafshah, Atefeh Ashtari, Sayeh Afshar, Keysan Pour Moghtader, Yasir Waheed   +5 more
doaj   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study

Nature and Science of Sleep, 2022
Jiye Lee,1,* Minjeong Kim,1,* Nambeom Kim,2 Yunjee Hwang,1 Kyung Hwa Lee,3,4 Jooyoung Lee,1 Yu Jin Lee,3 Seog Ju Kim1 1Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea ...
Lee J, Kim M, Kim N, Hwang Y, Lee KH, Lee J, Lee YJ, Kim SJ   +7 more
doaj