Results 41 to 50 of about 1,154,940 (248)
Journal of the Indian Academy of GeriatricsBackground: Data pertaining to dual malignancies in the geriatric population are not only sparse but also heterogeneous. The present study evaluated the pattern of care for geriatric dual malignancy patients at a tertiary care center.
Yamini Bachheti +7 more
doaj +1 more source
Clinicopathological features of lymphoma/leukemia patients carrying both BCL2 and MYC translocations
Haematologica, 2009 Background Lymphoid neoplasm with 18q21.3/BCL2 and 8q24/MYC translocation to immunoglobulin (IG) genes as dual-hit lymphoma/leukemia is very rare and known to have a poor clinical outcome.Design and Methods To clarify the clinicopathological ...
Naoto Tomita +14 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Double Troubles – Managing a Series of Cases with Dual Primary Malignancies
Medical Journal of Dr. D.Y. Patil VidyapeethThe reported incidence of multiple primary malignant tumor (MPMT) is between 0.734% and 11.7%. Double primary malignancy is the occurence of second primary malignant tumor of another organ in patients with a known malignant tumor.
Santhosh Nanjappa +4 more
doaj +1 more source
Synchronous dual malignancy: Successfully treated cases [PDF]
, 2007 The occurrence of a second malignancy in a patient with a known malignant tumour is not uncommon. Synchronous primary malignancies are still unusual We are presenting two cases treated successfully at our centre.
Agrawal, Rashi, Rashi Agrawal
core +1 more source
Dual-mode protocol latency comparison.
, 2022 Dual-mode protocol latency comparison.
Shuyang Ren (14053541) +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source