Dual Active Galactic Nuclei: Precursors of Binary Supermassive Black Hole Formation and Mergers
The Astrophysical JournalThe presence of dual active galactic nuclei (AGNs) on scales of a few tens of kiloparsecs can be used to study merger-induced accretion on supermassive black holes (SMBHs) and offer insights about SMBH mergers, using dual AGNs as merger precursors.
Vida Saeedzadeh +5 more
doaj +1 more source
The maximum number of cusps of an algebraic plane curve, and enumeration of self-dual curves [PDF]
, 1917 M. W. Haskell
openalex +1 more source
A 200 kb/s 36 µw True Random Number Generator Based on Dual Oscillators for IOT Security Application [PDF]
, 2023 Chengying Chen, Shuhui Li, Changkun Song
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Facile dual-shot measurement of Schmidt number in type-0 and type-2 downconversion
Physical Review ResearchHigh-dimensional entangled states have now been identified as excellent candidates towards the enhancement of the bandwidth of quantum systems. A variety of methods exist that aim to certify and set the bounds to entanglement. However, rapid and accurate
Vikas S. Bhat +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
In situ analysis of FGFR2 mRNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients [PDF]
, 2017 Yasutoshi Kuboki +9 more
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