Results 81 to 90 of about 1,808,891 (305)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2005 We show that the Hawking-Page phase transition of a CFT on AdS_{d-1} weakly coupled to gravity has a dual bulk description in terms of a phase transition between a black string and a thermal gas on AdS_{d}.
Chamblin, A., Karch, A.
core +1 more source
Quasinormal modes and the phase structure of strongly coupled matter [PDF]
, 2016 We investigate the poles of the retarded Green's functions of strongly coupled field theories exhibiting a variety of phase structures from a crossover up to different first order phase transitions.
Janik, Romuald A. +2 more
core +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Microstructure-based model for the stress-strain relationship of hot-rolled dual-phase steel
工程科学学报, 2015 The microstructure of hot-rolled dual-phase steel was studied by scanning electron microscopy(SEM) and transmission electron microscopy(TEM). The volume fraction of each phase in the dual-phase steel was determined by Image-Pro Plus software.
PANG Qi-hang, TANG Di, ZHAO Zheng-zhi
doaj +1 more source
Computational multiheterodyne spectroscopy
, 2016 Dual comb spectroscopy allows for high-resolution spectra to be measured over broad bandwidths, but an essential requirement for coherent integration is the availability of a phase reference.
Burghoff, David, Hu, Qing, Yang, Yang
core +1 more source
Phase-stabilized dual-comb spectroscopy
, 2019 Optische Frequenzkämme zeichnen sich durch ihre phasenkohärenten, äquidistanten Laserlinien im Spektrum aus. Gegenwärtig werden sie unter anderem neben ihrem ursprünglichen Verwendungszweck für Frequenzmessungen verwendet. Molekulare Spektroskopie profitiert von der großen spektralen Bandbreite.
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Deformation behavior of designed dual-phase CuZr metallic glasses
Materials & Design, 2019 A nanometer-scale second phase in metallic glass (MG) heterostructures is effective to improve mechanical properties. In this work, molecular dynamics simulations are conducted to investigate the influence of various critical structural aspects such as ...
C.X. Peng +6 more
doaj +1 more source