Results 61 to 70 of about 982,655 (280)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Examination of generalized Tribonacci dual quaternions [PDF]
, 2023 This manuscript deals with introducing and discussing of a new type dual quaternions which are named generalized Tribonacci dual quaternions (GTDQ, for short).
İŞBİLİR, Zehra +2 more
core +1 more source
Helmert Transformation Problem. From Euler Angles Method to Quaternion Algebra
ISPRS International Journal of Geo-Information, 2020 The three-dimensional coordinate’s transformation from one system to another, and more specifically, the Helmert transformation problem, is one of the most well-known transformations in the field of engineering.
Stefania Ioannidou, George Pantazis
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dual-Quaternion Julia Fractals
, 2023 Fractals offer the ability to generate fascinating geometric shapes with all sorts of unique characteristics (for instance, fractal geometry provides a basis for modelling infinite detail found in nature). While fractals are non-euclidean mathematical objects which possess an assortment of properties (e.g., attractivity and symmetry), they are also ...
openaire +3 more sources
Modelling rigid origami with quaternions and dual quaternions
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2010 This paper examines the mathematical modelling of rigid origami, a type of origami where all the panels are rigid and can only rotate about crease lines. The rotating vector model is proposed, which establishes the loop-closure conditions among a group of characteristic vectors.
Wu, W, You, Z
openaire +3 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
ALGEBRAIC PROPERTIES OF BI-PERIODIC DUAL FIBONACCI QUATERNIONS [PDF]
, 2019 The purpose of the paper is to construct a new representation of dual quaternions called bi-periodic dual Fibonacci quaternions. These quaternions are originated as a generalization of the known quaternions in literature such as dual Fibonacci ...
Ekmekci, N., Gok, I, Ates, F.
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source