Results 51 to 60 of about 552,249 (310)
Women's principle and the issue of universal guilt in the novel 'Petruša i Miluša' by Petar Sarić [PDF]
Zbornik Radova Filozofskog Fakulteta u Prištini, 2020 The main characteristic of the novel Petruša i Miluša by Petar Sarić is an elaborate narrative scheme in the form of two voices, mother's and daughter's, two stories that flow and intertwine, and build a third-a story about a story.
Jeftimijević-Mihajlović Marija S.
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Descartes and the “metaphysical dualism”: Excesses in interpreting a classic [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2010 The article focuses on one of the most serious accusations brought against Descartes and modern philosophy, namely “the dualism of substance”. The accusers claim that the human body and soul were viewed as completely separate; consequently, their ...
Ştefan Afloroaei
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Defining a Relation between Phenomenal Knowledge and Physical Knowledge [PDF]
حکمت و فلسفهWhat is the relation between phenomenal concepts and physical concepts? In this paper, I try to propose an answer to this question with regard to the Knowledge Argument and Mary Thought Experiment.
Masoud Ghafari
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Petroleum Exploration and Development:: In the late 1970s, the theory of coal-formed gas began to take root, sprout, develop, and improve in China. After decades of development, a complete theoretical system was finally formed. The theory of coal-formed gas points out that coal measures are
Chengzao JIA +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Jak powstaje świadomość ciała? (How does consciousness of the body arise?) [PDF]
Analiza i Egzystencja, 2010 First sections of the article present the historical background of the twentieth century philosophy of the human body. Then the author analyzes main elements of Husserlian theory of the constitution of the body: constitution of visual, tactual and ...
Stanisław Judycki
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