Results 61 to 70 of about 149,447 (303)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Mind-Body-Technology: ‘Nosce te Ipsum’ and a theory of prosthetic ‘trialism’ [PDF]
, 2018 This chapter will discuss a profound and fundamental interrelationship between mind, body and technology in terms of what it means to be ‘human’, or, what ‘being’ human might mean.
Slevin, Tom
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Women's principle and the issue of universal guilt in the novel 'Petruša i Miluša' by Petar Sarić [PDF]
Zbornik Radova Filozofskog Fakulteta u Prištini, 2020 The main characteristic of the novel Petruša i Miluša by Petar Sarić is an elaborate narrative scheme in the form of two voices, mother's and daughter's, two stories that flow and intertwine, and build a third-a story about a story.
Jeftimijević-Mihajlović Marija S.
doaj
Conservation of Energy is Relevant to Physicalism [PDF]
, 2007 I argue against Barbara Montero's claim that Conservation of Energy has nothing to do with physicalism. I reject her reconstruction of the argument for physicalism from CoE, and offer an alternative reconstruction that better captures the intuitions of ...
Koksvik, Ole
core +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Descartes and the “metaphysical dualism”: Excesses in interpreting a classic [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2010 The article focuses on one of the most serious accusations brought against Descartes and modern philosophy, namely “the dualism of substance”. The accusers claim that the human body and soul were viewed as completely separate; consequently, their ...
Ştefan Afloroaei
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Elisabeth of Bohemia as a Naturalistic Dualist [PDF]
, 2018 Elisabeth was the first of Descartes' interlocutors to press concerns about mind-body union and interaction, and the only one to receive a detailed reply, unsatisfactory though she found it.
Janssen-Lauret, Frederique
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