Results 71 to 80 of about 149,447 (303)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The coal-formed gas theory promoting China from a gas-poor country to a major gas-producing country in the world

open access: yesPetroleum Exploration and Development
:: In the late 1970s, the theory of coal-formed gas began to take root, sprout, develop, and improve in China. After decades of development, a complete theoretical system was finally formed. The theory of coal-formed gas points out that coal measures are
Chengzao JIA   +8 more
doaj   +1 more source

Rhetorical Dualism and the Orthodox/Heterdox Distinction in Economics [PDF]

open access: yes
This paper attempts to combine elements of the approaches of two influential economists, Sheila Dow and Deirdre McCloskey and expands on previous work (2005) on Dow’s concept of dualism.
Andrew Mearman
core  

Fission, First Person Thought, and Subject-body Dualism [PDF]

open access: yes, 2017
In “The Argument for Subject Body Dualism from Transtemporal Identity Defended” (PPR 2013), Martine Nida-Rümelin (NR) responded to my (PPR 2013) criticism of her (2010) argument for subject-body dualism.
Ludwig, Kirk
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Jak powstaje świadomość ciała? (How does consciousness of the body arise?) [PDF]

open access: yesAnaliza i Egzystencja, 2010
First sections of the article present the historical background of the twentieth century philosophy of the human body. Then the author analyzes main elements of Husserlian theory of the constitution of the body: constitution of visual, tactual and ...
Stanisław Judycki
doaj  

Editor\u27s Introduction [PDF]

open access: yes, 2011
The publication of Michelle Voss Roberts\u27 Dualities: A Theology of Difference (Louisville, KY: Westminster John Knox Press, 2010) has been welcomed by many scholars in the field of Hindu-Christian studies as one of the best books in comparative ...
Malkovsky, Brad
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sucedâneos à ética clássica: reflexões sobre o agir humano e o além do homem nietzscheano Surrogates for the classical ethics: Nietzsche's reflections on the human actions and his concept of overman

open access: yesTrans/Form/Ação, 2005
Baseado nas reflexões de Nietzsche sobre a ação humana e o além-do-homem, este artigo discute sua crítica demolidora à ética clássica à luz do contexto mais amplo do século XIX de desconstrução dos valores éticos enraizados até então.
Mariana Paolozzi Sérvulo da Cunha
doaj   +1 more source

Embodied ways of knowing. [PDF]

open access: yes, 2004
In this article I present an argument for `embodied ways of knowing' as an alternative epistemological strategy, drawing on feminist research and embodied experience.
Barbour, Karen
core   +1 more source

Home - About - Disclaimer - Privacy