Results 71 to 80 of about 552,249 (310)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

FENOMEN KAVRAMININ MENŞEİ ÜZERİNE DÜŞÜNCELER

open access: yesFelsefe Dünyası, 2010
Bu yazıda asıl amacım fenomen kavramının gelişimini genel bir bakış açısıyla aydınlatmaktır. Bu amaçla, formlar ve duyusal dünya arasındaki Platoncu sınırdan söz ettim.
Servet Gözetlik
doaj  

Inheritance Law between Common and Civil Law - As exemplified by life-long support contracts

open access: yesEtnoantropološki Problemi, 2009
The dualism between common law and civil law in Serbia has been examined in theoretical and factographical ethnological and legal literature, yet this problem in the sphere of inheritance law has been considered mostly within the context of inequality ...
Jadranka Đorđević Crnobrnja
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Red and Black World

open access: yesStudies in Ancient Art and Civilization, 2014
The red and black formed in Egypt a système antinomique (B. Mathieu). Desheret (the desert) represented the sphere of the wild and the natural, while kemet (alluvial land) signified cultivated and civilised areas.
Andrzej Ćwiek
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

How I Lost My Mind and Found the Meaning of “Life” [PDF]

open access: yesIntegral Review, 2007
By integrating philosophical rigor with practical examples and personal history and revelation, the author shares how he ended his quest to understand the concepts of life, mind, and soul and resolved the mind-body problem.
Herb Koplowitz
doaj  

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