Results 111 to 120 of about 45,447 (286)
An Optimal Ubiquitin-Proteasome Pathway in the Nervous System: The Role of Deubiquitinating Enzymes
Frontiers in Molecular Neuroscience, 2014 The Ubiquitin-Proteasome Pathway (UPP), which is critical for normal function in the nervous system and is implicated in various neurological diseases, requires the small modifier protein ubiquitin to accomplish its duty of selectively degrading short ...
Gorica eRistic +2 more
doaj +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
Chemistry – A European Journal, EarlyView.ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Liberalism and the Distinctiveness of Religious Belief [PDF]
, 2020 Finding the appropriate sweet spot for religion’s role in the state and how state action may affect the lives of religious people continues to be elusive.
Greene, Abner S.
core +1 more source
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, EarlyView.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
Transient thermal modelling of green anode cooling in the aluminium industry
The Canadian Journal of Chemical Engineering, EarlyView.Summary of the methodology. Abstract Anodes, which are used in electrolytic aluminium production, are made by mixing dry aggregate (petroleum coke, rejected anodes, and butts) with coal tar pitch, compacting the resulting paste (green anode), and baking (baked anode). After compaction, the anodes are cooled to maintain their structural integrity before
Mohammadhossein Dabaghi +2 more
wiley +1 more source
Strict and non-strict negative concord in Hungarian: A unified analysis [PDF]
, 2018 Surányi (2006) observed that Hungarian has a hybrid (strict + non-strict) negative concord system. This paper proposes a uniform analysis of that system within the general framework of Zeijlstra (2004, 2008) and, especially, Chierchia (2013), with the ...
Szabolcsi, Anna
core
A Simple Regeneration Process Using a CO2‐Switchable‐Polarity Solvent for Cellulose Hydrogels
ChemSusChem, Volume 18, Issue 6, March 15, 2025.The effect of transformation of the anion chemical structure on cellulose solubility by flowing CO2 gas into aqueous pyrrolidinium hydroxide solutions was investigated. The changes in anion structure allowed for the modulation of cellulose solubility in aqueous pyrrolidinium hydroxide solutions, thus establishing a simple and safe cellulose ...
Arata Matsui +5 more
wiley +1 more source
Human Vaccines & ImmunotherapeuticsRecently, immunotherapy has been a key therapeutic strategy for cancer. Deubiquitinating enzymes (DUBs), which are protein-modifying enzymes, have a crucial role in the pathogenesis of cancer, autoimmune diseases, and inflammation.
Xia Chen +7 more
doaj +1 more source
Feminist Anthropology, EarlyView.Abstract This article explores how Afro‐Brazilian communities in Pernambuco respond to state‐led industrial development through culturally rooted practices of resistance and repair. Drawing on archival and ethnographic research in the coastal municipalities of Cabo de Santo Agostinho and Ipojuca, this study traces the effects of Brazil's large‐scale ...
Shelly Annette Biesel
wiley +1 more source
Diterpenoid Diversity across Land Plants
Helvetica Chimica Acta, EarlyView.Here we bridge the knowledge of diterpene chemical diversity, biosynthesis, and evolution from nonvascular mosses and liverworts to that known from vascular plants. ABSTRACT The diverse array of diterpenoid natural products stems from the ease of manipulating the promiscuity of diterpene cyclases.
Anita Berg +2 more
wiley +1 more source