Results 131 to 140 of about 45,447 (286)
CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING [PDF]
, 2017 Endocytosis is a process by which cells internalize membrane proteins to remove them from the plasma membrane, allowing cells to regulate the cell surface expression of transmembrane proteins.
Sirisaengtaksin, Natalie +1 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley +1 more source
The EMBO JournalThe ubiquitination and proteasome-mediated degradation of Hypoxia Inducible Factors (HIFs) is central to metazoan oxygen-sensing, but the involvement of deubiquitinating enzymes (DUBs) in HIF signalling is less clear.
Tekle Pauzaite +3 more
doaj +1 more source
Spin waves in coupled YIG/Co heterostructures
, 2017 We investigate yttrium iron garnet (YIG)/cobalt (Co) heterostructures using broadband ferromagnetic resonance (FMR). We observe an efficient excitation of perpendicular standing spin waves (PSSWs) in the YIG layer when the resonance frequencies of the ...
Althammer, Matthias +11 more
core +1 more source
The IceShark, an effective method for sampling plankton under sea ice
Limnology and Oceanography: Methods, EarlyView.Abstract Seasonal sea ice plays a crucial role in shaping coastal ecosystem dynamics throughout the circumpolar region. Of particular interest to oceanographers is the ice‐ocean interface which functions as a multidimensional habitat, supporting both sympagic algae and pelagic phytoplankton in the under‐ice surface waters.
Eleanor A. Barry +4 more
wiley +1 more source
No App, No Entry: Conceptualizing Digital Technology Captivity in Service Access
Psychology &Marketing, EarlyView.ABSTRACT We introduce Digital Technology Captivity (DTC), a form of consumer vulnerability that arises when digital technologies become the mandatory gateway to essential services. When access is tied to systems that feel unfamiliar, complex, or intimidating—and when preferred alternatives are limited—consumers may experience heightened vulnerability ...
Carolyn Wilson‐Nash +4 more
wiley +1 more source
Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization
Macromolecular Rapid Communications, EarlyView.Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou +6 more
wiley +1 more source
Evangelical Christians in Canadian National Television News, 1994–2004: A Frame Analysis [PDF]
, 2007 Recent surveys have shown that most evangelical Christians in Canada believe that the news media treat them unfairly. This study empirically tested the validity of the evangelicals’ charge against the media by examining the frames used in the nightly ...
Haskell, David M.
core +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Frontiers in PharmacologyBackgroundOvarian cancer is a highly aggressive malignancy with limited therapeutic options and a poor prognosis. Deubiquitinating enzymes (DUBs) have emerged as critical regulators of protein ubiquitination and proteasomal degradation, influencing ...
Fang Qiu +8 more
doaj +1 more source