Results 131 to 140 of about 103,945 (310)

Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa, Midena, Edoardo, Miglionico, Giacomo, Parrozzani, Raffaele, Perrini, Pierdavide, Pilotto, Elisabetta, Pulze, Serena, Testi, Ilaria   +7 more
core   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou, Hoon Kim, John Watkinson, Vinay Varadan   +3 more
core   +1 more source

Quality‐adjusted life years in the presence and absence of organized mammographic screening using data from BreastScreen Norway

International Journal of Cancer, EarlyView.
What's New? Although mammographic screening can reduce breast cancer mortality and extend life, some studies have found a negative impact on net quality‐adjusted life years (QALYs). Here, the authors estimated net QALYs associated with biennial mammographic screening for women aged 50–69 years in Norway under various scenarios.
Rick Groeneweg, Nicolien T. van Ravesteyn, Lindy M. Kregting, Giske Ursin, Solveig Hofvind, Nataliia Moshina   +5 more
wiley   +1 more source

CARCINOMA DUCTAL IN SITU: GENERALIDADES, DIAGNÓSTICO, TRATAMIENTO Y CONTROVERSIAS

Revistas Argentina de Medicina, 2018
El carcinoma ductal in situ (CDIS) constituye, en lugar de una sola entidad, un grupo heterogéneo de lesiones con diferente potencial de malignidad y se lo considera un verdadero precursor del cáncer.
Carlos E Muñoz Medina, Luis D Alemán Frías, Milvis P Fleitas Moreno, Lizbeth B Tovar Duque, Irene Alvez, Oscar A Hurtado Patiño, Jairo Basetta, Milgaris P Fleitas Moreno, Elvis Polanco   +8 more
doaj   +2 more sources

Challenges in the future of cancer screening

International Journal of Cancer, EarlyView.
Abstract The purpose of cancer screening is to reduce mortality, and ideally incidence, from the cancer screened for. Until recently, cancer screening has been offered to all persons in pre‐defined sex‐ and age‐groups. The exception is lung screening which is targeted to high‐risk individuals.
Elsebeth Lynge, Berit Andersen, Stig E. Bojesen, Lone Kjeld Petersen, Mickael Bech, Martin Bøgsted, Mie Seest Dam, Søren Egstrand, Anne Mette Fløe Hvass, Camilla J. Kobylecki, Kristina Lång, Mads Nielsen, Giorgi Paolo Rossi, Michael Stenger, Ilse Vejborg, Future of Cancer Screening Working Group, Vibe Munk Bertelsen, Janne Bigaard, Karen Omann Binderup, Lennart Friis‐Hansen, Stine Bisgaard Greve, Jessica Xin Hjaltelin, Rikke Hedegaard Jensen, Gitte Jessing, Pia Kirkegaard, Mette Hartmann Nonboe, Tina Bech Olesen, Katrine Stolberg, Signe Bülow Therkildsen, Mette Kielsholm Thomsen   +29 more
wiley   +1 more source

Ductal carcinoma in situ

, 2017
Ductal carcinoma in situ (DCIS) represents some 25% of screen-detected breast neoplasia. Established clinical practice includes surgery, radiotherapy and endocrine therapy, to reduce the likelihood of DCIS recurrence or progression to invasive breast cancer.
Stacey A. Carter, Sarah E. Pinder, Alastair M. Thompson   +2 more
openaire   +2 more sources

Age‐specific breast cancer incidence by subtype, TNM stage and screening status in Sweden 2008–2019 estimated with multiple imputation

International Journal of Cancer, EarlyView.
What's New? Breast cancer incidence in women increases with age, but which subtypes contribute the most at different ages remains unclear. Incidence patterns of breast cancer subtypes are typically under‐reported in population‐based studies due to a high proportion of cases lacking subtype information.
Leo Gkekos, Katrín Ásta Gunnarsdóttir, Keith Humphreys, Irma Fredriksson, Anna L. V. Johansson   +4 more
wiley   +1 more source

Current approach and future perspective for ductal carcinoma in situ of the breast

Japanese Journal of Clinical Oncology, 2017
This review presents an overview of the current treatment approaches, problems with overdiagnosis and potential future management strategies for ductal carcinoma in situ of the breast.
C. Kanbayashi, H. Iwata
semanticscholar   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source