Results 61 to 70 of about 1,028,846 (258)

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Dust and elemental abundances in Damped Ly alpha absorbers [PDF]

, 1997
The effects of the dust on the determination of elemental abundances in damped Ly alpha (DLA) absorbers are investigated. Relations between the observed abundances measured in the gas phase and the overall abundances (gas plus dust) are derived as a function of dust-to-gas ratio, metallicity, element-to-element abundance pattern, average extinction ...
arxiv   +1 more source

Dust-regulated galaxy formation and evolution:A new chemodynamical model with live dust particles

, 2015
Interstellar dust plays decisive roles in the conversion of neutral to molecular hydrogen (H_2), the thermodynamical evolution of interstellar medium (ISM), and the modification of spectral energy distributions (SEDs) of galaxies.
Bekki, Kenji
core   +1 more source

Modeling Dust and Starlight in Galaxies Observed by Spitzer and Herschel: The KINGFISH Sample [PDF]

, 2020
Interstellar dust and starlight are modeled for the galaxies of the project "Key Insights on Nearby Galaxies: A Far-Infrared Survey with Herschel." The galaxies were observed by the Infrared Array Camera and the Multiband Imaging Photometer for Spitzer ...
Aniano, G., Armus, L., Helou, G.
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Cold Dust in Kepler's Supernova Remnant

, 2003
The timescales to replenish dust from the cool, dense winds of Asymptotic Giant Branch stars are believed to be greater than the timescales for dust destruction.
Braun R., H. L. Morgan, Hildebrand R. H., Kinugasa K., L. Dunne, M. G. Edmunds, R. J. Ivison, S. A. Eales, Sandell G.   +8 more
core   +1 more source

Dust in Spiral Galaxies: Comparing Emission and Absorption to Constrain Small-Scale and Very Cold Structures [PDF]

, 1999
The detailed distribution of dust in the disks of spiral galaxies is important to understanding the radiative transfer within disks, and to measuring overall dust masses if significant quantities of dust are either very opaque or very cold.
Alton P. B., Block D. L., Cesarsky C., Charmandaris V., Donovan L. Domingue, Elmegreen D. M., Haas M., Hildebrand R. H., Hummel E., Kessler M. F., Klaas U., Krugel E., Lagache G., Lemke D., Lloyd B. D., Raymond E. White III, Rowan-Robinson M., Siebenmorgen R., Stuart D. Ryder, Tuffs R. J., William C. Keel, Wozniak H.   +21 more
core   +2 more sources

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Aeolian Dust and Dust Deposits

Journal of Arid Environments, 1988
In Earth science history, numerous subjects, such as pollen and freshwater diatoms have been studied from first a geological point of view, then in relation to the presentday environment. This is the case for dust; loess deposit studies began as far back as 1880 and included many international publications on the subject, but scientific works ...
  +7 more sources

Dust-Dust Collisional Charging and Lightning in Protoplanetary Discs [PDF]

, 2009
We study the role of dust-dust collisional charging in protoplanetary discs. We show that dust-dust collisional charging becomes an important process in determining the charge state of dust and gas, if there is dust enhancement and/or dust is fluffy, so that dust surface area per disc volume is locally increased.
arxiv   +1 more source