Results 101 to 110 of about 1,668 (251)

Graphene (0002)/Diamond (111) Heterojunction with High Piezoresistive Response

open access: yesAdvanced Science, EarlyView.
Graphene/diamond heterostructures show promise as silicon alternatives for semiconductors, but high‐quality integration is challenging. Thermal electron irradiation enables covalent bonding; lonsdaleite acts as an intermediate. The heterostructure exhibits a high piezoresistive response (gauge factor −1149) associated with electron‐rich layers and ...
Xueyu Zhang   +10 more
wiley   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

Hints of Planet Formation Signatures in a Large-cavity Disk Studied in the AGE-PRO ALMA Large Program

open access: yesThe Astrophysical Journal
Detecting planet signatures in protoplanetary disks is fundamental to understanding how and where planets form. In this work, we report dust and gas observational hints of planet formation in the disk around 2MASS J16120668-301027, as part of the Atacama
Anibal Sierra   +21 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

The ALMA Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO). X. Dust Substructures, Disk Geometries, and Dust-disk Radii

open access: yesThe Astrophysical Journal
We perform visibility fitting to the dust continuum Band 6 1.3 mm data of the 30 protoplanetary disks in the Atacama Large Millimeter/submillimeter Array Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO) Large Program.
Miguel Vioque   +20 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

Testing He ii Emission from Wolf–Rayet Stars as a Dust Attenuation Measure in Eight Nearby Star-forming Galaxies

open access: yesThe Astrophysical Journal
The ability to determine galaxy properties such as masses, ages, and star formation rates robustly is critically limited by the ability to measure dust attenuation accurately.
Daniel Maschmann   +4 more
doaj   +1 more source

Optimizing Stratification in Binary Colloidal Supraparticles

open access: yesAdvanced Science, EarlyView.
Supraparticles from binary particle populations show stratification when dried at high Péclet numbers. In spray‐dried systems at high initial particle concentration and fast drying conditions optimal combinations of particle size ratios and volume fractions that produce maximal stratification are found both in experiment and simulation, contrasting the
Frederic Rudlof   +5 more
wiley   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

open access: yesAdvanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song   +10 more
wiley   +1 more source

Hints of Disk Substructure in the First Brown Dwarf with a Dynamical Mass Constraint

open access: yesThe Astrophysical Journal Letters
We present high-resolution Atacama Large Millimeter/submillimeter Array (ALMA) observations at 0.89 mm of the Class II brown dwarf 2MASS J04442713+2512164 (2M0444), achieving a spatial resolution of 0 $\mathop{.}\limits^{^{\prime\prime} }$ 046 (∼6.4 au ...
Alejandro Santamaría-Miranda   +16 more
doaj   +1 more source

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