Results 91 to 100 of about 1,574,380 (286)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

MIRI spectrophotometry of GN-z11: Detection and nature of an optical red continuum component

Astronomy & Astrophysics
We present new MIRI F560W, F770W, and F1000W imaging of the galaxy GN-z11 at a redshift of 10.603. We report a significant detection (14σ) in the F560W and F770W images, and a marginal detection (3.2σ) in the F1000W filter.
Crespo Gómez A., Colina L., Pérez-González P. G., Álvarez-Márquez J., García-Marín M., Alonso-Herrero A., Annunziatella M., Bik A., Bosman S., Bunker A. J., Labiano A., Langeroodi D., Rinaldi P., Östlin G., Boogaard L., Gillman S., Barro G., Finkelstein S. L., Leung G. C. K.   +18 more
doaj   +1 more source

Toward measuring supermassive black hole masses with interferometric observations of the dust continuum

, 2022
This work focuses on active galactic nuclei (AGNs) and on the relation between the sizes of the hot dust continuum and the broad-line region (BLR). We find that the continuum size measured using optical/near-infrared interferometry (OI) is roughly twice ...

core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Synthesis imaging of the DR 21(OH) cluster. I - Dust continuum and C(O-18) emission

The Astrophysical Journal, 1991
Maps at 7″ resolution of 2.7 mm continuum and J=1→0 C 18 O emission have been made of the DR 21(OH) molecular cloud core. Three compact regions, all of which appear to be actively forming stars, have been detected. Two components, each measuring ∼12,000 AU in size, containing ∼400-500 M ⊙ of material and encompassing H 2 O masers, dominate the most ...
Jeffrey G. Mangum, Alwyn Wootten, Lee G. Mundy   +2 more
openaire   +1 more source

Unusually High Gas-to-dust Ratios Observed in High-redshift Quiescent Galaxies

The Astrophysical Journal Letters
Tracking the cold molecular gas contents of galaxies is critical to understand the interplay between star formation and galaxy growth across cosmic time. Observations of the long-wavelength dust continuum, a proxy for the cold gas, are widely used in the
Justin S. Spilker, Katherine E. Whitaker, Desika Narayanan, Rachel Bezanson, Sarah Bodansky, Vincenzo R. D’Onofrio, Robert Feldmann, Andy D. Goulding, Jenny E. Greene, Mariska Kriek, Yuanze Luo, David J. Setton, Katherine A. Suess, Arjen van der Wel, Margaret E. Verrico, Christina C. Williams, Charity Woodrum, Po-Feng Wu   +17 more
doaj   +1 more source

The Plant‐to‐Plant Circular Strategy: Coupling Photodegradation and Phytoremediation With Plant‐Based Nanomaterials for Plastic Degradation

Advanced Science, EarlyView.
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu, Lena Ciric, Yuheng Wang, Ziru Pei, Manpreet Bhatti   +4 more
wiley   +1 more source

exoALMA. IV. Substructures, Asymmetries, and the Faint Outer Disk in Continuum Emission

The Astrophysical Journal Letters
The exoALMA Large Program targeted a sample of 15 disks to study gas dynamics within these systems, and these observations simultaneously produced continuum data at 0.9 mm (331.6 GHz) with exceptional surface brightness sensitivity at high angular ...
Pietro Curone, Stefano Facchini, Sean M. Andrews, Leonardo Testi, Myriam Benisty, Ian Czekala, Jane Huang, John D. Ilee, Andrea Isella, Giuseppe Lodato, Ryan A. Loomis, Jochen Stadler, Andrew J. Winter, Jaehan Bae, Marcelo Barraza-Alfaro, Gianni Cataldi, Nicolás Cuello, Daniele Fasano, Mario Flock, Misato Fukagawa, Maria Galloway-Sprietsma, Himanshi Garg, Cassandra Hall, Andrés F. Izquierdo, Kazuhiro Kanagawa, Geoffroy Lesur, Cristiano Longarini, Francois Menard, Ryuta Orihara, Christophe Pinte, Daniel J. Price, Giovanni Rosotti, Richard Teague, Gaylor Wafflard-Fernandez, David J. Wilner, Lisa Wölfer, Hsi-Wei Yen, Tomohiro C. Yoshida, Brianna Zawadzki   +38 more
doaj   +1 more source