Results 51 to 60 of about 611,299 (306)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Durable and ductile double-network material for dust control [PDF]
, 2020 Dust generation is a world-wide issue due to its serious deleterious effects on the environment, human health and safety, and the economy. Although various dust suppression methods have been used for decades, some critical drawbacks in state-of-the-art ...
Carlson, L +6 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
环境与职业医学During the career life cycle, workers may face various health problems such as occupational injuries, occupational diseases, and work-related diseases.
Xiaojun ZHU, Yishuo GU, Jingguang FAN
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
环境与职业医学BackgroundVolatile organic compounds (VOCs) in exhaled breath are closely associated with respiratory diseases and are linked to various metabolic reactions in the human body.
Rui GAO +7 more
doaj +1 more source
Assessment of Workers' Exposure to Cement Dust, in Concrete Batching Unit of a Dam Project before and after Control Measures [PDF]
, 2014 Background: The importance of clean air in industrial workplaces is well known. Cement dust, due to its silica content, is very dangerous. The aims of this study were to assess and control the release of cement dust from silos of concrete batching units ...
Ebrahim Darvishi, Afshar Moradi,
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
环境与职业医学BackgroundWorkers in the cable manufacturing industry are exposed to high-speed machinery and equipment for a long time, coupled with heavy workload, which poses significant risks to their physical health.
Ting XU +7 more
doaj +1 more source
Dust accretion and destruction in galaxy groups and clusters [PDF]
, 2010 We examine the dust distribution around a sample of 70,000 low redshift galaxy groups and clusters derived from the Sloan Digital Sky Survey. By correlating spectroscopically identified background quasars with the galaxy groups we obtain the relative ...
Adelman-McCarthy +65 more
core +3 more sources