Results 41 to 50 of about 4,499,156 (300)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Minor effect of physical size sorting on iron solubility of transported mineral dust [PDF]

open access: yes, 2011
Observations show that the fractional solubility of Fe (FS-Fe, ratio of dissolved to total Fe) in dust aerosol increases dramatically from ~0.1% in regions of high dust mass concentration to 80% in remote regions where concentrations are low.
G. Fones   +39 more
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The formation of molecular hydrogen in the interstellar medium [PDF]

open access: yes, 2010
H2 is the most abundant molecule in the interstellar medium and forms on the surface of interstellar dust grains. Laboratory studies have been conducted of HD formation on a dust grain analogue, which is a highly-oriented pyrolytic graphite surface ...
Islam, F.
core  

ELPIS: Accelerated Metal and Dust Enrichment in a Protocluster Core at z ≈ 8

open access: yesThe Astrophysical Journal Letters
We present a study of the metal, dust, and molecular gas content in galaxies within the A2744-z7p9OD protocluster at z  ≈ 7.88. We focus on two galaxy groups—the Quintet and the Chain—which are covered by the Emission-Line Protocluster Imaging Survey ...
Hideki Umehata   +19 more
doaj   +1 more source

Impact of mineral dust on cloud formation in a Saharan outflow region [PDF]

open access: yesAtmospheric Chemistry and Physics, 2012
We present a numerical modelling study investigating the impact of mineral dust on cloud formation over the Eastern Mediterranean for two case studies: (i) 25 September 2008 and (ii) 28/29 January 2003. In both cases dust plumes crossed the Mediterranean
L. Smoydzin   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From Dust to Planets: Planet formation through a dust dynamics lens [PDF]

open access: yes, 2021
PhD thesisPlanetesimal formation, the process by which dust is collected into kilometre-sized bodies, is a fundamental stage in planetary system formation. In this thesis the earliest stages of planetesimal formation are studied.
Lovascio, Francesco
core   +3 more sources

Tracing the History of Obscured Star Formation with the SIMBA Cosmological Galaxy Evolution Simulation

open access: yesThe Astrophysical Journal
We explore the cosmic evolution of the fraction of dust-obscured star formation predicted by the simba cosmological hydrodynamic simulations featuring an on-the-fly model for dust formation, evolution, and destruction.
Dhruv T. Zimmerman   +3 more
doaj   +1 more source

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