DXR: A Toolkit for Building Immersive Data Visualizations [PDF]
IEEE Transactions on Visualization and Computer Graphics, 2019 This paper presents DXR, a toolkit for building immersive data visualizations based on the Unity development platform. Over the past years, immersive data visualizations in augmented and virtual reality (AR, VR) have been emerging as a promising medium for data sense-making beyond the desktop.
Ronell Sicat +2 more
exaly +7 more sources
Antitumor Activity of Liposomal Nanoparticles Co-Encapsulating Ceramides and Doxorubicin in In Vitro Nucleolin-Expressing Neuroblastoma Models [PDF]
CellsBackground: Neuroblastoma (NB) causes about 15% of cancer deaths in childhood. Recently, we suggested cell-surface nucleolin (NCL) as a novel target for preclinical therapy against NB.
Veronica Bensa +9 more
doaj +2 more sources
Decrease of the DXR-induced genotoxicity and nongenotoxic effects of Theobroma cacao revealed by micronucleus assay [PDF]
Brazilian Journal of Biology, 2021 This study evaluated the genotoxicity of lyophilized glycolic extract of Theobroma cacao Linné seeds (TCL), using the micronucleus assay in bone marrow of mice. The interaction between TCL and doxorubicin (DXR) was also analyzed. Experimental groups were
M. F. G. Boriollo +7 more
doaj +7 more sources
Anti-CD133-grafted single-walled carbon nanotubes as doxorubicin carrier [PDF]
Biological Procedures OnlineBackground Advances in nanomedicine have spurred interest in antibody-conjugated carbon nanotubes for targeted cancer therapy. CD133, a marker enriched in chemoresistant cancer stem cells, presents a strategic target for precision drug delivery.
Elham Momeni +4 more
doaj +2 more sources
Daixie recipe ameliorates diet-induced MASH in mice via activating PI3K/AKT and Keap1/Nrf2 signaling [PDF]
Frontiers in EndocrinologyBackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is a highly prevalent liver disease that can progress to cirrhosis and hepatocellular carcinoma. Despite its growing clinical burden, effective therapies remain limited. Daixie recipe (DXR)
Xiaoli He +18 more
doaj +2 more sources
N-Acylated sulfonamide congeners of fosmidomycin lack any inhibitory activity against DXR [PDF]
Bioorganic and Medicinal Chemistry Letters, 2015 The antibiotic fosmidomycin (3a) is an inhibitor of the non-mevalonate pathway for isoprenoid biosynthesis. Four analogues in which an acylated sulfonamide group is substituting for its phosphonate moiety have been synthesized in a fruitless effort to preserve one negative charge in order to increase the accompanying affinity for 1-deoxy-d-xylulose 5 ...
Bharat Gadakh +2 more
exaly +4 more sources
Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major [PDF]
Avicenna Journal of Phytomedicine, 2018 Objective: The aim of the present study was to evaluate the possible protective effect of Plantago major (P. major) extract against doxorubicin (DXR)-induced renal inflammation in rats.
Nazanin Entezari Heravi +11 more
doaj +1 more source
Cortical hand bone porosity and its association with distal radius fracture in middle aged and elderly women. [PDF]
PLoS ONE, 2013 OBJECTIVE: Reduced bone mineral density (BMD), assessed by Dual Energy X-ray absorptiometry (DXA), is a well-known risk factor for fragility fracture. A large proportion of patients with fracture have only slightly reduced BMD.
Alvilde Dhainaut +3 more
doaj +1 more source
Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Doxorubicin (DXR)-induces glomerular atrophy and fibrosis in rat kidneys. The objective of the current study was to investigate the protective effects of valsartan on DXR-induced glomerular toxicity and its mechanisms of actions in rats ...
Hai-Xia Liu, Jin Li, Qi-Xiong Li
doaj +1 more source
Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice. [PDF]
PLoS ONE, 2015 Advances in cancer treatment utilizing multiple chemotherapies have dramatically increased cancer survivorship. Female cancer survivors treated with doxorubicin (DXR) chemotherapy often suffer from an acute impairment of ovarian function, which can ...
Jenna Kropp +5 more
doaj +1 more source