Results 11 to 20 of about 7,254 (221)

Evaluation of a Diagnostic Reasoning Program (DxR): Exploring Student Perceptions and Addressing Faculty Concerns

open access: yesJournal of Interactive Media in Education, 1998
: Clinical reasoning is essentially a problem-solving process, in which medical students must learn to gather and interpret data, generate hypotheses and make decisions.
Deborah A. Bryce   +3 more
doaj   +3 more sources

DxR Case Study

open access: yesCommunications of the Association for Information Systems, 2000
FROM THE PREFACE TO THE CASE STUDY: In July 1998, Hurley Myers, President of DxR Development Group, stared at the gray plastoid brain lying on the desk before him.
Carol Saunders, Blake Ives
openaire   +4 more sources

Novel insights into structure–function mechanism and tissue‐specific expression profiling of full‐lengthdxr gene fromCymbopogon winterianus

open access: yesFEBS Open Bio, 2015
The 1‐deoxy‐d‐xylulose‐5‐phosphate reductoisomerase (DXR; EC1.1.1.267), an NADPH‐dependent reductase, plays a pivotal role in the methylerythritol 4‐phosphate pathway (MEP), in the conversion of 1‐deoxy‐d‐xylulose‐5‐phosphate (DXP) into MEP.
Kamalakshi Devi   +4 more
doaj   +2 more sources

Biomineralization of primary carbonate cements: a new biosignature in the fossil record from the Anisian of Southern Italy

open access: yesLethaia, EarlyView., 2021
Biomineralization is a generic term used to indicate biological‐mediated mineral formation. In carbonate mineralization, nucleation of crystals can be: (1) controlled directly by the organisms, like in the skeletal formation of most metazoans; (2) induced by microbial communities, by indirect precipitation mediated by their metabolic activities; or (3)
Adriano Guido   +4 more
wiley   +1 more source

Doxorubicin-induced vascular toxicity--targeting potential pathways may reduce procoagulant activity. [PDF]

open access: yesPLoS ONE, 2013
Previous study in mice using real-time intravital imaging revealed an acute deleterious effect of doxorubicin (DXR) on the gonadal vasculature, as a prototype of an end-organ, manifested by a reduction in blood flow and disintegration of the vessel wall.
Irit Ben Aharon   +8 more
doaj   +1 more source

Nano-Resveratrol: A Promising Candidate for the Treatment of Renal Toxicity Induced by Doxorubicin in Rats Through Modulation of Beclin-1 and mTOR

open access: yesFrontiers in Pharmacology, 2022
Background: Although doxorubicin (DXR) is one of the most used anticancer drugs, it can cause life-threatening renal damage. There has been no effective treatment for DXR-induced renal damage until now.Aim: This work aims at examining the potential ...
Ahlam M. Alhusaini   +7 more
doaj   +1 more source

Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axis

open access: yesCancer Cell International, 2021
Background Osteosarcoma (OS) is a common type of bone malignancy that often occurs in children and adolescents. Chemoresistance is a huge barrier to cancer therapy.
Huapeng Guan   +6 more
doaj   +1 more source

Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

open access: yesScientific Reports, 2020
Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration.
Paul Cray   +3 more
doaj   +1 more source

Projected lung areas using dynamic X-ray (DXR) [PDF]

open access: yesEuropean Journal of Radiology Open, 2020
Dynamic X-ray (DXR) provides images of multiple phases of breath with less radiation exposure than CT. The exact images at end-inspiratory or end-expiratory phases can be chosen accurately.To investigate the correlation of the projected lung area (PLA) by dynamic chest X-ray with pulmonary functions.One hundred sixty-two healthy volunteers who received
Takuya Hino   +13 more
openaire   +3 more sources

Anti-inflammatory effects of saxagliptin and vildagliptin against doxorubicin-induced nephrotoxicity in rats: attenuation of NLRP3 inflammasome up-regulation and tubulo-interstitial injury

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: The clinical use of the chemotherapeutic drug, doxorubicin (DXR), is significantly limited by its extensive multi-organ toxicity.
Rasha Ezzat Mostafa   +2 more
doaj   +1 more source

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