Results 121 to 130 of about 298,539 (305)

Dynamic Capabilities Theory : A review [PDF]

Dynamic capabilities (DCs) are higher-level competences enabling organisations to integrate, build, and reconfigure resources to address and shape dynamic ...
Nayernia, H.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dynamic capabilities in times of economic crisis. A vision of success in international markets. [PDF]

Heliyon, 2023
Ledesma-Chaves P, Jorge Arenas-Gaitán.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Imovation in shaping dynamic capabilities of organisations

Management, 2016
The underlying assumption of the article is that imitation is as important as innovation when creating a long-term competitive advantage, and that a systematic, strategic approach to imitation is necessary to ensure efficient and effective innovation ...
Krzakiewicz Kazimierz, Cyfert Szymon
doaj   +1 more source

Entrepreneurship and Dynamic Capabilities: A Review, Model and Research Agenda

, 2006
The emergent literature on dynamic capabilities and their role in value creation is riddled with inconsistencies, overlapping definitions, and outright contradictions.
Per Davidsson, Harry J. Sapienza, Sapienza, Harry J., Shaker A. Zahra, Zahra, Shaker A., Davidsson, Per   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Creating Value with Acquisition Based Dynamic Capabilities (ABDC): A Study of Mergers and Acquisitions in the Regulated Energy Industry

, 2016
M&A research has consistently shown that value is destroyed for a majority of acquirers. Despite initial small positive gains at deal announcement, within a year of closing the transaction a majority of acquirers experience overall negative returns ...
Berard, Rich
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Micro-foundations of dynamic capabilities to facilitate university technology transfer. [PDF]

PLoS One, 2023
Ma Z, Augustijn KD, De Esch IJP, Bossink BAG.   +3 more
europepmc   +1 more source