Results 101 to 110 of about 298,539 (305)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dynamic capabilities from an institutionalist viewpoint

open access: yesCadernos EBAPE.BR
The purpose of this paper is to elucidate the effects of strategic, technical and institutional response, in the perspective of dynamic capability facing environmental changes, considering that the literature has few references on how institutional ...
José Bonfim Albuquerque Filho   +2 more
doaj   +1 more source

The role of supply chain management in improving performance of Jordanian small and medium enterprises [PDF]

open access: yesProblems and Perspectives in Management
Supply chain management practices are always helpful for multinational enterprises in increasing their growth. However, there has always remained an open debate about which practices are helpful for small and medium enterprises (SMEs).
Ahmad Almohtaseb   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Dynamic Capabilities in the German financial services industry

open access: yesEuropean Journal of Management Issues, 2018
Purpose. The purpose of this work is to investigate processes constituting to Dynamic Capabilities in companies of the German financial services industry. Design/Method/Approach. Exploratory with a qualitative approach and a multiple case study method.
Tobias Oeser
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Influence of Dynamic Capabilities in Creating Disruptive Innovation

open access: yes
The aim of this paper is to demonstrate the influence of Dynamic Capabilities in creating Disruptive Innovation. For doing so the concepts of Dynamic Capabilities and Disruptive Innovation are reviewed.
Čiutienė, Rūta   +1 more
core   +1 more source

Dynamic capabilities, Marketing Capability and Organizational Performance

open access: yesBBR: Brazilian Business Review, 2017
The goal of the study is to investigate the influence of dynamic capabilities on organizational performance and the role of marketing capabilities as a mediator in this relationship in the context of private HEIs in Brazil.
Adriana Roseli Wünsch Takahashi   +3 more
doaj  

The Role of Dynamic Capabilities and Customer Knowledge in Affecting Knowledge Management Capabilities on Performance (Case Study: The Gas Company of Yazd) [PDF]

open access: yesمدیریت راهبردی دانش سازمانی, 2019
Considering the significance of customer knowledge and management capability, this research is mainly aimed at investigating the effects of knowledge management capabilities on the organizational performance mediated by dynamic capabilities and customer ...
Amir Reza Konjkav Monfared   +2 more
doaj  

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