Results 61 to 70 of about 1,292,127 (280)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Dynamic capabilities within organizations

RAE: Revista de Administração de Empresas, 2017
The development and use of dynamic capabilities has been a central issue in strategic management and organizational studies over the last decade. While providing a dynamic approach to the first wave of resource-based views on firm operations, dynamic ...
Joaquín Alegre
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Microfoundations of dynamic capabilities for innovation: a review and research agenda [PDF]

, 2017
This paper provides a conceptual overview of the microfoundations of dynamic capabilities for innovation. A critical evaluation of dynamic capabilities theory highlights its contested nature and significant limitations in its application.
Fallon-Byrne, Lucy, Harney, Brian
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A Model for Technological Capability Improvement in Technology-Based Firms by Using Explanatory Mixed Method (The Sample of Iranian Avionic Firms) [PDF]

بهبود مدیریت, 2013
Aerial Industry with huge market size (100 billion $) and high growth rate (5% annually) is one of the strategic and high technology industries. Avionic sector and its technologies have a significant share of this industry.
Manochehr Manteghi, Seyyed Habibollah Tabatabaiean, Payam Hanafizadeh, Mohammad Naghizadeh   +3 more
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Exploring small and medium enterprise performance through dynamic capability perspective

The Southern African Journal of Entrepreneurship and Small Business Management
Background: Small and medium enterprises (SMEs) are crucial to both global and national economies. They create jobs, boost competitiveness and drive economic growth.
Dotty Wimpertiwi, Muhtosim Arief, Firdaus Alamsjah, Rini Setiowati   +3 more
doaj   +1 more source

The Strategic Role of Digital Capabilities in Organizational Performance: A Systematic Literature Review [PDF]

International Journal of Information Science and Management
Recognizing the complexity of digital capabilities (DC) is critical in the evolving digital environment. This study explores the conceptualization, dimensions, and strategic impact of DC on organizations by adopting a systematic literature review (SLR ...
Candraningrat Candraningrat, Tanti Handriana, Muchammad Saifuddin   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source