Results 61 to 70 of about 1,307,758 (299)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Human capabilities and firm performance in women-owned micro and small-medium enterprises: The mediating role of substantive and dynamic capabilities

open access: yesSmall Business International Review
Dynamic capabilities are widely recognized as a catalyst for firm performance yet there is a dearth of research on how dynamic capabilities work with human and substantive capabilities to contribute to firm performance particularly in women-owned micro ...
Antoinette Flynn   +2 more
doaj   +1 more source

Entrepreneurial initiatives as a microfoundation of dynamic capabilities [PDF]

open access: yes, 2018
Purpose - The purpose of this paper is to show how entrepreneurial initiatives in organizations serve as a microfoundation of dynamic capabilities and, thus, foster change in organizations.
Mahringer, Christian A., Renzl, Birgit
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Performance-limit criteria for the design of fast-response servo-actuation systems [PDF]

open access: yes, 1970
Analysis of a typical nonlinear electrohydraulic servo-model establishes the dynamic-performance capabilities of servo-actuation ...
Zeller, J. R.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Dynamic capabilities, expert and entrepreneurial learning

open access: yesSouth African Journal of Business Management, 2014
This article focuses on how managers sense and seize opportunities for learning and developing dynamic capabilities in organisations. An approach of building process theory from cases traces learning events in the technological innovation approaches of ...
C. J. Lecler, J. Kinghorn
doaj   +1 more source

The Role of Dynamic Capabilities While Expanding a Nonprofit Abroad [PDF]

open access: yes, 2018
The purpose of this senior capstone is to research and fully comprehend the dynamic capabilities field of strategic management as well as the experience students at Bryant University’s Zhuhai campus are having.
Feehan, Alison
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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