Results 81 to 90 of about 9,289,283 (320)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2022 The study offers a nuanced view of multi-stakeholder networks (MSNs) as settings for capability development through learning. Unlike numerous studies of capability development in networks being framed through a resource-based perspective, the study ...
Polina Baranova, Baranova, P.
core +1 more source
Cogent Business & Management, 2021 The purpose of this research is (1) to examine the integration impact of IT assets (e.g., intangible IT resources, IT capability, and IT flexibility) on core competency, and (2) to explore the mediating effect of core competency on the relationship ...
Lahcene Makhloufi +4 more
doaj +1 more source
PLoS ONEIn the context of digital economy, both the process and boundaries of open innovation performance are changing, and digital transformation has become an important factor for enterprises to realize open innovation performance in a complex and changing ...
Peiyao Qiu, Benrui Chang
semanticscholar +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Climate Resilience and SustainabilityThis study examines the moderating role of market orientation between corporate environmental sustainability (CES) and firm performance dimensions within the energy sector.
Benjamin Kweku Acolatse +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
IT DYNAMIC CAPABILITY DEVELOPMENT IN THE CONTEXT OF DATA GENESIS CAPABILITY [PDF]
Dynamic Capabilities are often considered as the factor justifying the different degrees of success of organizations in turbulent environment. However Dynamic Capability development remains a difficult issue to research, with a paucity of work directly ...
Claudio Vitari
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source