Results 31 to 40 of about 45,946 (274)
The Phylogenetics of Dynamics in DNA Clamp Proteins [PDF]
Structure, 2014 Using HXMS to measure protein dynamics, Fang and colleagues (in this issue of Structure) probe the dynamics of processivity clamp proteins from all kingdoms of life. The proteins have similar structures but divergent sequences. Their results show conserved dynamics correlating with primary functions and divergent dynamics for divergent functions.
Balasubramaniam, Deepa +1 more
openaire +2 more sources
eLife, 2014 Individuals vary in their responses to stroke and trauma, hampering predictions of outcomes. One reason might be that neural circuits contain hidden variability that becomes relevant only when those individuals are challenged by injury.
Akira Sakurai +2 more
doaj +1 more source
Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current
Frontiers in Behavioral Neuroscience, 2010 Linear leak currents have been implicated in the regulation of neuronal excitability, generation of neuronal and network oscillations, and network state transitions.
Shunbing Zhao +4 more
doaj +1 more source
Cell Reports, 2022 Summary: Protein machines undergo conformational motions to interact with and manipulate polymeric substrates. The Sec translocase promiscuously recognizes, becomes activated, and secretes >500 non-folded preprotein clients across bacterial cytoplasmic ...
Srinath Krishnamurthy +10 more
doaj +1 more source
Dynamics of a clamped–clamped microbeam resonator considering fabrication imperfections [PDF]
Microsystem Technologies, 2014 We present an investigation into the static and dynamic behavior of an electrostatically actuated clamped---clamped polysilicon microbeam resonator accounting for its fabrication imperfections, which are commonly encountered in similar microstructures.
Bataineh, Ahmad M., Younis, Mohammad I.
openaire +2 more sources
Synchronisation through nonreciprocal connections in a hybrid hippocampus microcircuit
Frontiers in Neural Circuits, 2013 Synchronisation among neurons is thought to arise from the interplay between excitation and inhibition; however, the connectivity rules that contribute to synchronisation are still unknown.
Markus M Hilscher +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Atrial fibrillation (AF) is the most common cardiac arrhythmia. About 5–15% of AF patients have a mutation in a cardiac gene, including mutations in KCNA5, encoding the Kv1.5 α-subunit of the ion channel carrying the atrial-specific ultrarapid delayed ...
Sarah Hilderink +5 more
doaj +1 more source
Diversity of intrinsic frequency encoding patterns in rat cortical neurons : mechanisms and possible functions [PDF]
, 2010 Extracellular recordings of single neurons in primary and secondary somatosensory cortices of monkeys in vivo have shown that their firing rate can increase, decrease, or remain constant in different cells, as the external stimulus frequency increases ...
Robinson, Hugh P. C. +8 more
core +1 more source
Patch-clamp and multi-electrode array electrophysiological analysis in acute mouse brain slices
STAR Protocols, 2021 Summary: Patch-clamp and multi-electrode array electrophysiology techniques are used to measure dynamic functional properties of neurons. Whole-cell and cell-attached patch-clamp recordings in brain slices can be performed in voltage-clamp and current ...
Kevin M. Manz +3 more
doaj +1 more source
Frontiers in Computational Neuroscience, 2014 Spinal motoneurons may display a variety of firing patterns including bistability between repetitive firing and quiescence and, more rarely, bistability between two firing states of different frequencies.
Marin eManuel +2 more
doaj +1 more source