Results 71 to 80 of about 1,736,262 (298)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

NI-MOD-P-RRT*: A threshold-free sampling-based path planning algorithm for unmanned surface vehicles in dynamic environments

open access: yesAIMS Electronics and Electrical Engineering
In this paper, we propose a threshold-free multi-objective dynamic rapidly-exploring random tree algorithm (NI-MOD-P-RRT*) for unmanned surface vehicles in unknown dynamic environments.
Yunlai Fu   +4 more
doaj   +1 more source

Benchmark generator for CEC 2009 competition on dynamic optimization [PDF]

open access: yes, 2008
Evolutionary algorithms(EAs) have been widely applied to solve stationary optimization problems. However, many real-world applications are actually dynamic.
Beyer, H   +7 more
core   +1 more source

Experimental study on population-based incremental learning algorithms for dynamic optimization problems [PDF]

open access: yes, 2005
Copyright @ Springer-Verlag 2005.Evolutionary algorithms have been widely used for stationary optimization problems. However, the environments of real world problems are often dynamic. This seriously challenges traditional evolutionary algorithms.
Yang, S, Yao, X
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Dynamic trust models for ubiquitous computing environments [PDF]

open access: yes, 2002
A significant characteristic of ubiquitous computing is the need for interactions of highly mobile entities to be secure: secure both for the entity and the environment in which the entity operates. Moreover, ubiquitous computing is also characterised by
English, C.   +4 more
core   +1 more source

Constructing dynamic test environments for genetic algorithms based on problem difficulty [PDF]

open access: yes
This article is posted here with permission from IEEE - Copyright @ 2004 IEEEIn recent years the study of dynamic optimization problems has attracted an increasing interest from the community of genetic algorithms and researchers have developed a variety
Yang, S
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Real-Time Adaptive Target Tracking via Inverse Kinematics Optimization in Stabilized Systems

open access: yesIEEE Access
To keep a target item inside their field of view, two-axis gimbal systems are designed to dynamically compensate for any movements that may occur, whether such movements originate from the target itself or from the platform on which the device is mounted.
Abderahman Kriouile   +3 more
doaj   +1 more source

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