Results 81 to 90 of about 3,923,177 (307)

Dynamic response solutions of unsaturated soil foundation using soil-water characteristic curve considering deformation effects

Yantu gongcheng xuebao
To investigate the dynamic response of unsaturated soils under moving loads, a new soil-water characteristic curve (SWCC) model is established considering the deformation caused by applied load based on the traditional V-G SWCC model. Using this modified
HU Jing 1 , JIN Linlian 1, LÜ Zhihao 1, ZHANG Jiakang 1, BIAN Xuecheng 2
doaj   +1 more source

Propeller dynamic and aeroelastic effects [PDF]

, 1980
Various aspects of propeller blade dynamics are considered including those factors which are exciting the blades and the dynamic response of the blades to the excitations.
Mccormick, B. W.
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Dynamic response characteristics of the initial support structure of the double-track tunnel blasting

Shenzhen Daxue xuebao. Ligong ban
In the process of blasting excavation of the later excavated tunnel, it is crucial to ensure the safety of blasting vibration in the first excavated tunnel.
HUANG Chuansheng, YANG Xin, LIN Jihua, XU Hao, HU Deyu, REN Kaifu   +5 more
doaj   +1 more source

Dynamic correlations of the Coulomb Luttinger liquid

, 2001
The dynamic density response function, form-factor, and spectral function of a Luttinger liquid with Coulomb electron-electron interaction are studied with the emphasis on the short-range electron correlations.
A. Holas, A. Luther, B. Tanatar, D. Agosti, D.C. Mattis, F. Brosens, F. Brosens, F. Brosens, F. Brosens, F. Toigo, F. Toigo, F. Toigo, F.D.M. Haldane, F.D.M. Haldane, G. Cuniberti, H.J. Schulz, J. Hubbard, J. Voit, J.M. Luttinger, J.T. Devreese, J.T. Devreese, K.S. Singwi, K.S. Singwi, L. Calmels, L. Calmels, L. Calmels, M. Johnson, Q.P. Li, Q.P. Li, Q.P. Li, Q.P. Li, R.K. Moudgil, S. Das Sarma, S. Tomonaga, T. Hasegawa, V. A. Sablikov, V.A. Sablikov, V.A. Sablikov, Yasha Gindikin   +38 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Test results from a dynamic model dynaflex rotor [PDF]

, 1985
A one-fifth scale dynamic model of the Sikorsky Dynaflex rotor was tested in hover and in forward flight conditions in a wind tunnel. The Dynaflex rotor features an advanced composite structure which flexes to provide a constant speed universal joint ...
Goodman, R. K., Niebanck, C. F.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source