Results 71 to 80 of about 221,094 (291)

Dedisatria_175100009_static routing dan dynamic routing

open access: yes, 2019
Perkembangan IT saat ini menuju dengan konsep-kosenp social networkingnya, openess, share, colaborations, mobile, easy maintenance, one click, terdistribusi / tersebar, scalability, Concurency dan Transparan, Saat ini terdapat trend teknologi yang masih terus digali dalam penelitian-penelitian para pakar IT di dunia, yaitu Cloud Computing.Routing ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Lightweight Routing Protocol for Named Data Networking [PDF]

open access: yesJisuanji kexue yu tansuo
Named data networking (NDN) is a novel network architecture that revolves around information-centric principles. In order to acquire global routing information within the network, typical NDN routing protocols rely on data synchronization mechanisms to ...
ZOU Bowen, SONG Tian, LI Tianlong, YANG Yating
doaj   +1 more source

Motion-Based Routing and Transmission Power Control in Wireless Body Area Networks

open access: yesIEEE Open Journal of the Communications Society, 2020
Wireless body area networks (WBANs) are characterized by large fluctuations in channel losses due to body shadowing. These fluctuations follow the patterns of the user's body movements.
Garrett Newell, Gustavo Vejarano
doaj   +1 more source

Dynamic programming algorithm for the vehicle routing problem with time windows and EC social legislation [PDF]

open access: yes, 2009
In practice, apart from the problem of vehicle routing, schedulers also face the problem of nding feasible driver schedules complying with complex restrictions on drivers' driving and working hours.
Kok, A. Leendert   +3 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Dynamic Routing Between Capsules

open access: yes, 2017
A capsule is a group of neurons whose activity vector represents the instantiation parameters of a specific type of entity such as an object or an object part. We use the length of the activity vector to represent the probability that the entity exists and its orientation to represent the instantiation parameters.
Sabour, Sara   +2 more
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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