Results 81 to 90 of about 221,094 (291)

Current State of Dynamic Vehicle Routing Problems Solved by Ant Colony Optimization Algorithm

Tehnički Glasnik, 2021
Dynamic Vehicle Routing Problem is a more complex version of Vehicle Routing Problem, closer to the present, real-world problems. Heuristic methods are used to solve the problem as Vehicle Routing Problem is NP-hard. Among many different solution methods,
Luka Olivari, Goran Đukić
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Implementation and performance of a new multiple objective dynamic routing method for multiexchange networks

Journal of Telecommunications and Information Technology, 2003
The paper describes new developments of a multiple objective dynamic routing method (MODR) for circuit-switched networks previously presented, based on the periodic calculation of alternative paths for every node pair by a specialised bi-objective ...
Lúcia Martins
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hierarchical Multi-Stage Attention and Dynamic Expert Routing for Explainable Gastrointestinal Disease Diagnosis

Diagnostics
Purpose: Gastrointestinal (GI) illness demands precise and efficient diagnostics, yet conventional approaches (e.g., endoscopy and histopathology) are time-consuming and prone to reader variability. This work presents GID-Xpert, a deep learning framework
Muhammad John Abbas, Hend Alshaya, Wided Bouchelligua, Nehal Hassan, Inzamam Mashood Nasir   +4 more
doaj   +1 more source

Steady state analysis of balanced-allocation routing

, 2002
We compare the long-term, steady-state performance of a variant of the standard Dynamic Alternative Routing (DAR) technique commonly used in telephone and ATM networks, to the performance of a path-selection algorithm based on the "balanced-allocation ...
Anagnostopoulos, Aris, Kontoyiannis, Ioannis, Upfal, Eli   +2 more
core   +1 more source

Cluster Before You Hallucinate: Approximating Node-Capacitated Network Design and Energy Efficient Routing [PDF]

, 2014
We consider circuit routing with an objective of minimizing energy, in a network of routers that are speed scalable and that may be shutdown when idle. We consider both multicast routing and unicast routing.
Krishnaswamy, Ravishankar, Nagarajan, Viswanath, Pruhs, Kirk, Stein, Cliff   +3 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

A dynamic routing scheme for underwater acoustic sensor networks in submarine disaster applications

Frontiers in Marine Science
IntroductionThe ocean economy serves as a critical engine for the development of human society and economy, and its stable growth is of utmost importance.
Peng Jiang, Hao Wang, Zhiwen Xiong
doaj   +1 more source