Results 71 to 80 of about 1,797,412 (279)

Unsupervised Band Selection Method Based on Importance-Assisted Column Subset Selection

IEEE Access, 2019
Band selection is an important preprocessing technique for hyperspectral images to select a band subset with representative information and low correlation. However, most methods focus on removing redundant components without loss of original information,
Xiaoyan Luo, Zhiqi Shen, Rui Xue, Han Wan   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Bi-Level Optimization in a Transport Network

Cybernetics and Information Technologies, 2015
This paper applies a bi-level formalism for the optimal control of an urban transportation network. The well known store-and-forward model in traffic control is utilized in order to increase the control space of the optimization problem.
Stoilov Todor, Stoilova Krasimira, Papageorgiou Markos, Papamichail Ioannis   +3 more
doaj   +1 more source

Decision-Making for the Autonomous Navigation of Maritime Autonomous Surface Ships Based on Scene Division and Deep Reinforcement Learning

Sensors, 2019
This research focuses on the adaptive navigation of maritime autonomous surface ships (MASSs) in an uncertain environment. To achieve intelligent obstacle avoidance of MASSs in a port, an autonomous navigation decision-making model based on hierarchical ...
Xinyu Zhang, Chengbo Wang, Yuanchang Liu, Xiang Chen   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Nonlinear Model Predictive Control for a Dynamic Positioning Ship Based on the Laguerre Function

Journal of Marine Science and Engineering
In this paper, we present a novel nonlinear model predictive control (NMPC) algorithm based on the Laguerre function for dynamic positioning ships to solve the problems of input saturation, unknown time-varying disturbances, and heavy computation.
Xiaobin Qian, Helong Shen, Yong Yin, Dongdong Guo   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Multiple strut-deformation patterns based analytical elastic modulus of sandwich BCC lattices

Materials & Design, 2019
This paper proposed an analytical methodology to predict the mechanical properties of sandwich body-centred cubic (BCC) lattice structures. Based on the Timoshenko beam theory, the multiple strut-deformation patterns were first introduced in the ...
Yunhui Yang, Meijuan Shan, Libin Zhao, Dexuan Qi, Jianyu Zhang   +4 more
doaj   +1 more source