Hallmarks of the pre-disease state: prevention and control of the pre-disease state, a tipping point between health and disease. [PDF]
Chen P, Liu X, Liu R, Chen L.
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Disequilibrium Dynamics: An Empirical Study [PDF]
Kawasaki, Seiichi +2 more
openaire
Correction: Dynamical analysis of scabies delayed epidemic model with second-order global stability. [PDF]
Fadhal E +6 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Qualia as control-theoretic constructs for autonomous agents: event phase space as an action-oriented semantic safety layer. [PDF]
Suvorov V.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Numerical analysis & modelling in the life sciences: a topical collection in honor of Ezio Venturino. [PDF]
Bulai IM, Cavoretto R, De Rossi A.
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Multiscale Ordinal-Pattern Dynamics and Temporal Symmetries in a Photonic Neuron with Single and Dual Delayed Feedback. [PDF]
Feiveson J +3 more
europepmc +1 more source

