Results 71 to 80 of about 529,550 (317)

Human Brain Networks: Spiking Neuron Models, Multistability, Synchronization, Thermodynamics, Maximum Entropy Production, and Anesthetic Cascade Mechanisms

open access: yesEntropy, 2014
Advances in neuroscience have been closely linked to mathematical modeling beginning with the integrate-and-fire model of Lapicque and proceeding through the modeling of the action potential by Hodgkin and Huxley to the current era.
Wassim M. Haddad   +2 more
doaj   +1 more source

Toric dynamical systems [PDF]

open access: yes, 2007
Toric dynamical systems are known as complex balancing mass action systems in the mathematical chemistry literature, where many of their remarkable properties have been established.
Craciun, Gheorghe   +3 more
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Dynamical Behavior of a Rigid Body with One Fixed Point (Gyroscope). Basic Concepts and Results. Open Problems: a Review

open access: yesJournal of Applied and Computational Mechanics, 2015
The study of the dynamic behavior of a rigid body with one fixed point (gyroscope) has a long history. A number of famous mathematicians and mechanical engineers have devoted enormous time and effort to clarify the role of dynamic effects on its movement
Svetoslav Ganchev Nikolov   +1 more
doaj   +1 more source

Celulární automat a CML systémy [PDF]

open access: yes, 2018
The main aim of this thesis is the study of cellular automata and discrete dynamical systems on a lattice. Both tools, cellular automata as well as dynamical systems on a lattice are introduced and elementary properties described.
Štula, Václav
core  

ŽAMPA’S SYSTEMS THEORY: A COMPREHENSIVE THEORY OF MEASUREMENT IN DYNAMIC SYSTEMS

open access: yesActa Polytechnica, 2018
The article outlines in memoriam Prof. Pavel Žampa’s concepts of system theory which enable us to devise a measurement in dynamic systems independently of the particular system behaviour. From the point of view of Žampa’s theory, terms like system time, system attributes, system link, system element, input, output, sub-systems, and state variables are ...
Renata Rychtáriková   +2 more
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Theoretical Principles of Multiscale Spatiotemporal Control of Neuronal Networks: A Complex Systems Perspective

open access: yesFrontiers in Computational Neuroscience, 2018
Success in the fine control of the nervous system depends on a deeper understanding of how neural circuits control behavior. There is, however, a wide gap between the components of neural circuits and behavior.
Nima Dehghani, Nima Dehghani
doaj   +1 more source

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