Results 131 to 140 of about 41,917 (266)
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
The FEBS Journal, EarlyView.In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source
, 2012 (A) Schematic representation of the T-shaped dynamin tetramers or ‘dimer of dimers’ [26], [27] which explains the inter-domain interactions between the GED, middle Domain and GTPase domain.
Swagata Chakraborty (188090) +2 more
core +1 more source
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
The FEBS Journal, EarlyView.Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
New Phytologist, EarlyView.Overview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Louise Hambücken +2 more
wiley +1 more source
Visualizing the GTPase activity of dynamin with nanobodies
, 2016 Dynamin is a large GTPase that mediates membrane fission at the last step of clathrin mediated endocytosis through helical polymerization and membrane constriction of the neck of the clathrin coated vesicle triggered by GTP hydrolysis.
Galli, Valentina
core +1 more source
Molecular Oral Microbiology, EarlyView.Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai +7 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Rice has developed an efficient system for manganese (Mn) uptake, mediated by two distinct transporters, OsNramp5 and OsMTP9. These transporters exhibit polar localization at the root exodermis and endodermis; however, the mechanisms underlying their polar localization and their role in Mn uptake remain unclear.
Noriyuki Konishi, Jian Feng Ma
wiley +1 more source
The Development of Isoform-Selective Dynamin Modulators
, 2014 Dynamin I (dynI) is essential for synaptic vesicle endocytosis in neurons, while dynamin II (dynII) is required for diverse cell functions (clathrin-mediated endocytosis, cytokinesis and actin dynamics).
Mariana, Anna
core
Ethanol-induced phosphorylation of dynamin is compromised in DKO hippocampus.
, 2013 (A) Immunoblot analysis of whole cell lysates from WT and DKO mice demonstrates increased expression of phosphorylated dynamin (pdyn) in WT, but not DKO hippocampus following ethanol treatment compared to saline controls.
Xiaoping Jiang (294305) +6 more
core +1 more source