Results 111 to 120 of about 41,917 (266)
Andrology, EarlyView.Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source
Dynamin localization in Caenorhabditis Elegans
, 2014 honors thesisCollege of ScienceBiologyErik JorgensenDynamin is a 100-KDa GTPase that is essential for endocytosis. The classic model of endocytosis is a sequential mechanism: first, cell membrane is bent and internalized via the formation of a clathrin ...
Prestgard-Duke, Michael
core
Endocytosis: How dynamin sets vesicles PHree!
, 1999 The dynamin GTPase is required for clathrin-dependent, receptor-mediated endocytosis. Exciting new studies have shown that dynamin's pleckstrin homology domain binds to phosphatidylinositol 4,5-bisphosphate in vivo, thus localising dynamin directly at ...
Paola Lo Surdo +5 more
core +1 more source
Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity. [PDF]
, 2015 Neurons express three closely related dynamin genes. Dynamin 1 has long been implicated in the regulation of synaptic vesicle recycling in nerve terminals, and dynamins 2 and 3 were more recently shown also to contribute to synaptic vesicle recycling in ...
Halpain, Shelley, Calabrese, Barbara
core +1 more source
SH3 Domains Differentially Stimulate Distinct Dynamin I Assembly Modes and G Domain Activity.
PLoS ONE, 2015 Dynamin I is a highly regulated GTPase enzyme enriched in nerve terminals which mediates vesicle fission during synaptic vesicle endocytosis. One regulatory mechanism involves its interactions with proteins containing Src homology 3 (SH3) domains.
Sai Krishnan +2 more
doaj +1 more source
British Journal of Haematology, EarlyView.Summary Diffuse large B‐cell lymphoma (DLBCL) is the most common aggressive non‐Hodgkin lymphoma and is characterized by substantial heterogeneity. This study aimed to develop a liquid–liquid phase separation (LLPS)‐related prognostic model to improve risk stratification.
Zhen‐Zhong Zhou +11 more
wiley +1 more source
, 2006 The dopamine D-3 receptor, which is highly enriched in nucleus accumbens (NAc), has been suggested to play an important role in reinforcement and reward.
Kittler, JT, Chen, GJ, Yan, Z, Moss, SJ
core
Dynamin architecture—from monomer to polymer
, 2010 Dynamins form a family of eukaryotic and prokaryotic proteins involved in membrane fission, fusion and restructuring. They have complex mechanisms of self-assembly, which are coupled to the tubulation and destabilization of lipid bilayers.
Jan Löwe +3 more
core +1 more source
A Dynamin Mutant Defines a Superconstricted Prefission State
Cell Reports, 2014 Dynamin is a 100 kDa GTPase that organizes into helical assemblies at the base of nascent clathrin-coated vesicles. Formation of these oligomers stimulates the intrinsic GTPase activity of dynamin, which is necessary for efficient membrane fission during
Anna C. Sundborger +5 more
doaj +1 more source
Endocytosis of KCa2.3 is dependent upon dynamin.
, 2013 A. GFP-tagged WT dynamin II and BLAP-tagged KCa2.3 were expressed in HEK293 cells. KCa2.3 was labeled at the plasma membrane with streptavidin-Alexa555 for 10 min at 4°C after which the cells were immediately imaged by live-cell confocal microscopy at 37°
Claudia A. Bertuccio (309866) +4 more
core +1 more source