Results 141 to 150 of about 35,988 (242)

Identification of Oncolytic Avian Reovirus Receptors in B16-F10 Cells and the Signaling-Mediated Pathways Involved in Viral Entry. [PDF]

Viruses
Hsu CY, Tu BY, Li JY, Liao TL, Wu YY, Lin CY, Chang YK, Munir M, Munir M, Liu HJ.   +9 more
europepmc   +1 more source

Non‐Contact Transspatial Regulatory Function of the Extracellular Matrix

Smart Medicine, Volume 5, Issue 4, August 2026.
Non‐contact transspatial regulation of the extracellular matrix (ECM), whereby the ECM remotely modulates cellular behavior without direct physical contact, is proposed and systematically investigated for the first time. This process involves multiple pathways and components, with actin‐dependent macropinocytosis playing a predominant role potentially.
Ting Cao, Chen Yang, Zhengyang Wang, Changmin Shao, Ziye Xu, Baode Chen, Jiayu Zhang, Yongcheng Wang, Fangfu Ye   +8 more
wiley   +1 more source

Membrane Constriction by Dynamin through GTP-Driven Conformational Changes from Coarse-Grained Molecular Dynamics Simulations. [PDF]

J Phys Chem Lett
Mahmood MI, Kubo S, Noguchi H, Okazaki KI.   +3 more
europepmc   +1 more source

HNRNPC Succinylation Influences the Neurodegeneration of Alzheimer's Disease Through YME1L1‐Mediated Mitochondrial Metabolism

Aging Cell, Volume 25, Issue 8, August 2026.
In Alzheimer's disease, SIRT5 downregulation enhances TRIM25‐mediated succinylation of HNRNPC at K50, increasing its stability. Stabilized HNRNPC upregulates YME1L1 expression via an m6A‐dependent mechanism, leading to OPA1 hydrolysis dysregulation, mitochondrial fission‐fusion imbalance, ROS overproduction, and neuronal death.
Xuewei Li, Fan Yang, Yuyan Jiang, Fei Zhao, Fan Liu   +4 more
wiley   +1 more source

Common themes in evoked ion channel translocation in neuroplastic and homeostatic plasticity. [PDF]

Front Pharmacol
Haan KD, Gaudet E, Fisher TE.
europepmc   +1 more source

Machine learning‐driven investigation on liquid–liquid phase separation‐related prognostic signature in diffuse large B‐cell lymphoma

British Journal of Haematology, Volume 209, Issue 2, Page 461-468, August 2026.
Summary Diffuse large B‐cell lymphoma (DLBCL) is the most common aggressive non‐Hodgkin lymphoma and is characterized by substantial heterogeneity. This study aimed to develop a liquid–liquid phase separation (LLPS)‐related prognostic model to improve risk stratification.
Zhen‐Zhong Zhou, Jia‐Chen Lu, Zhao Wang, Rong‐Hui Chen, Hai‐Long Li, Wan‐Ting Chen, Yu‐Ning Deng, Hui‐Juan Zhang, Yu Wang, Xuan‐Ye Zhang, Wei‐Juan Huang, Xiao‐Peng Tian   +11 more
wiley   +1 more source

The dynamin-related protein <i>Osdrp1c</i> plays an essential role in rice root elongation (<i>Oryza sativa</i> L.). [PDF]

Front Plant Sci
Hua Y, Guo Z, Jia L, Mu W, Li X, Li Q, Ma T, Chen Y, Qiu S, Zhang W, Ding W.   +10 more
europepmc   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

British Journal of Pharmacology, Volume 183, Issue 16, Page 5120-5147, August 2026.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon, Alessio Malacrida, Alessia Chiorazzi, Annalisa Canta, Paola Alberti, Valentina Alda Carozzi, Eleonora Pozzi, Virginia Rodriguez‐Menendez, Laura Cherchi, Valentina Fabbro, Lisa Pagani, Elisa Tonelli, Laura Tapella, Andrea Mattarei, Sara Palermo, Daniele Cartelli, Mario Mauri, Noemi Scimia, Serena Stanga, Dmitry Lim, Carla Distasi, Marta Delconti, Clizia Chinello, Patricia Morcillo, Maria Elena Pero, Francesca Bartolini, Guido Cavaletti, Cristina Meregalli   +27 more
wiley   +1 more source

Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life. [PDF]

Sci Adv
Landajuela A, Gomis Perez C, Bassereau P, Callan-Jones A, Karatekin E.   +4 more
europepmc   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, Volume 293, Issue 15, Page 4508-4532, August 2026.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source