Results 181 to 190 of about 63,555 (261)

Long‐Read Genome Sequencing Establishes Biallelic Pathogenic Variants in DNM1 With Distinct Functional Effects as the Cause of Early Infantile Developmental and Epileptic Encephalopathy

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 947-951, April 2026.
ABSTRACT Heterozygous de novo and inherited biallelic pathogenic variants in DNM1 have been reported in association with autosomal dominant (AD) and autosomal recessive (AR) developmental and epileptic encephalopathy, respectively, due to aberrant dynamin function or expression, with each inheritance pattern associated with a different mechanism of ...
Andy Drackley, Merlene Peter, Heba H. Akbari, Jelena Ivanisevic, Alexander Ing, Kelly Regan‐Fendt, Patrick McMullen, Kai Lee Yap   +7 more
wiley   +1 more source

Combinatorial treatment with donafenib and quercetin suppresses lipid metabolism in HepG2 cells by targeting the CREB1/DRP1/SREBP1 axis. [PDF]

Transl Cancer Res
Xiang L, Shi J, Huang X, Zhou S.
europepmc   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

The Role of the CLIC/GEEC Endocytic Pathway for Mechanophysical Transfection of DNA. [PDF]

J Gene Med
Weaver S, Lallow EO, Kyker-Snowman K, Jhumur NC, Gulley M, Roberts CC, Shreiber DI, Lin H, Maslow JN.   +8 more
europepmc   +1 more source

IL‐15 Links Muscle–Kidney Crosstalk to Preserving Podocyte Mitochondrial Fusion and Attenuating Diabetic Nephropathy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Objectives High glucose induces mitochondrial dysfunction in podocytes, contributing to the development of diabetic nephropathy (DN). There is increasing evidence that muscles play a protective role by secreting myokines into the kidneys. Here, we investigated how skeletal muscle influences podocyte health via muscle–kidney crosstalk.
Yin Li, Jialing Rao, Weiyan Lai, Yuxiang Sun, Hongchun Lin, Jun Zhang, Zengchun Ye, Zhaoyong Hu, Hui Peng   +8 more
wiley   +1 more source

Bovine coronavirus enters HRT-18 cells via membrane fusion and clathrin-mediated endocytosis in a low pH-, dynamin-, cholesterol-, microtubule-, Rab7-, and Rab11-dependent manner. [PDF]

J Virol
Chen C, Zhao L, Su N, Peng X, Song B, Zhang L, Guo K.   +6 more
europepmc   +1 more source

Dynamin (DMN) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Nanoceria Nanozyme Attenuates CoCl2‐Induced Oxidative Stress and Mitochondrial Dysfunction in H9c2 Cardiomyoblasts

Nano Select, Volume 7, Issue 4, April 2026.
This study shows that nanoceria protect H9c2 cardiomyoblasts from CoCl2‐induced chemical stress. Nanoceria reduces reactive oxygen species, preserves mitochondrial function, and regulates genes involved in antioxidant defense, intrinsic apoptosis, and inflammation. These findings highlight nanoceria's potential as a redox‐active nanozyme for protecting
Rukhsana Gul, Arwa Bazighifan, Mushtaq A. Dar, Shahid Nawaz, Assim A. Alfadda   +4 more
wiley   +1 more source

Heat shock proteins at the crossroads of endosomal trafficking pathways. [PDF]

Cell Biol Toxicol
Zuppini F, Renzullo L, Tornatore F, Poggio P, Brancaccio M.   +4 more
europepmc   +1 more source

Dynamin-2 [PDF]

, 2020
openaire   +1 more source