Results 181 to 190 of about 37,365 (212)

Mitochondrial dynamics and repair differences in two mouse models of Friedreich's ataxia

open access: yesThe Journal of Physiology, Volume 604, Issue 20, Page 8360-8378, 15 October 2026.
Abstract figure legend Differential mitochondrial remodelling in Friedreich's ataxia (FA)‐associated cardiomyopathy. Schematic summary of mitochondrial alterations in two mouse models of FA exhibiting distinct cardiac phenotypes. In cardiac/skeletal muscle‐specific MCK‐Cre frataxin knockout (FXN‐cKO) mice, which develop heart failure with reduced ...
Lili Salinas   +5 more
wiley   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

open access: yesPhysiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura   +3 more
wiley   +1 more source

DNM2 lipid binding drives centronuclear myopathy and represents a potential therapeutic target. [PDF]

open access: yesJCI Insight
Gómez-Oca R   +8 more
europepmc   +1 more source

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