Results 191 to 200 of about 63,555 (261)

Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 4, Page 947-960, April 2026.
ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán, András Czajlik, Brigitta Maruzs, Fanni Farkas, István Pap, Csilla Homonnay, Tomas Klumpler, Gyula Batta, Zoltán Gáspári, Bálint Péterfia   +9 more
wiley   +1 more source

A phosphoinositide switch from PI(4,5)P₂ to PI4P triggers endocytosis by inducing dynamin-mediated fission in secretory cells. [PDF]

Sci Adv
Guo X, Wei L, Kundu N, Shin W, Chan CY, Han S, Mohseni A, Molakarimi M, Sun M, Wu XS, Jin Y, Hinshaw JE, Wu LG.   +12 more
europepmc   +1 more source

The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos)

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Unlike humans, brown bears (Ursus arctos) uniquely preserve skeletal muscle mass and function during months of hibernation despite prolonged fasting and inactivity. We investigated how mitochondrial energetics respond in skeletal muscle to support this remarkable resilience.
Audrey Bergouignan, John Noone, Charlotte Brun, Laura Cussonneau, Alexandre Geffroy, Cecile Coudy‐Gandilhon, Isabelle Chery, Alina Lynn Evans, Jon Martin Arnemo, Jonas Kindberg, Guillemette Gauquelin‐Koch, Donal O'Gorman, Etienne Lefai, Fabrice Bertile   +13 more
wiley   +1 more source

Endoplasmic reticulum patterns insect cuticle nanostructure. [PDF]

J Cell Biol
Inagaki S, Wada H, Itabashi T, Itakura Y, Nakagawa R, Chen L, Murata K, Iwane AH, Hayashi S.   +8 more
europepmc   +1 more source

Disulfide Crosslinking Induces Rapid Degradation of Arc/Arg3.1 via Hsp70‐Mediated Ubiquitin Ligase Pathway

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So, In‐Kang Song, Yeon Jung Kim, Yeonjoo Lee, Yeon Seung Park, Hee‐Jung Kim, Kong‐Joo Lee, Eun Joo Song   +7 more
wiley   +1 more source

Binding of Bacillus subtilis dynamin-like protein DynA to the bacterial membrane is essential for effective phage defense. [PDF]

FEBS J
Shafqat S, Repnik U, Bramkamp M.
europepmc   +1 more source

DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organization. [PDF]

Mol Biol Cell
Dierlam C, Held S, Hastings J, Anyanwu L, Newman RH, Iyer J.   +5 more
europepmc   +1 more source

Traumatic Brain Injury and Endocytosis: Reduced Rodent Hippocampal Endocytosis Proteins and Human Clathrin Light Chain Polymorphisms Are Associated with Impaired Neurological Outcomes After TBI. [PDF]

Mol Neurobiol
Svirsky SE, Roberts A, Parry M, Henchir J, Dixon CE, Jackson TC, Chang Y, Conley Y, Puccio AM, Carlson SW.   +9 more
europepmc   +1 more source

Inhibition of autoantigen-induced B-cell receptor (BCR) internalization as a therapeutic strategy in diffuse large B cell lymphoma (DLBCL). [PDF]

Cell Death Dis
Górniak P, Polak A, Rams A, Kupcova K, Głodkowska-Mrówka E, Pilch Z, Miączyńska M, Nowis D, Gołąb J, Davis RE, Havranek O, Juszczyński P.   +11 more
europepmc   +1 more source

From bolinaquinone, a marine hydroxyquinone sesquiterpene, to naphthoquinones with clathrin inhibitory effects. [PDF]

RSC Med Chem
O'Brien NS, Ghods A, Xue J, Garson MJ, Yong KWL, Sakoff JA, Glibert J, Chircop M, Fink U, Haucke V, Robinson PJ, McCluskey A.   +11 more
europepmc   +1 more source