Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior [PDF]
Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the afferent circuitry that endogenously drives this neural activity and behavior, the downstream ...
Bhatti, Dionnet L. +6 more
core +3 more sources
Kappa Opioid Receptor and Dynorphin Signaling in the Central Amygdala Regulates Alcohol Intake [PDF]
Daniel W. Bloodgood +8 more
openalex +1 more source
Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K. +4 more
core +1 more source
Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A +64 more
core +2 more sources
The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj +1 more source
Expression of Kisspeptin, Neurokinin B, and Dynorphin During Pubertal Development in Female Sheep [PDF]
Eliana G Aerts +6 more
openalex +1 more source
Projection-Target-Defined Effects of Orexin and Dynorphin on VTA Dopamine Neurons
Circuit-specific signaling of ventral tegmental area (VTA) dopamine neurons drives different aspects of motivated behavior, but the neuromodulatory control of these circuits is unclear. We tested the actions of co-expressed lateral hypothalamic peptides,
Corey Baimel +3 more
doaj +1 more source
Characterization of big dynorphins from rat brain and spinal cord [PDF]
Xie Gx, A Goldstein
openalex +1 more source
Endogenous dynorphin in emotional control and stress response [PDF]
Christoph Schwarzer +6 more
openalex +1 more source
Individual differences in the neuropsychopathology of addiction. [PDF]
Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
core

