The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential
Frontiers in Molecular Neuroscience, 2017 Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
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Dynorphin immunocytochemistry in the rat central nervous system [PDF]
, 1982 Henry Khachaturian +5 more
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N,N‐diallyl‐tyrosyl substitution confers antagonist properties on the κ‐selective opioid peptide [D‐Pro10]dynorphin A(1–11) [PDF]
, 1988 Jean Edouard Gairin +5 more
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Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]
, 1997 Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M. +3 more
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[3H]dynorphin a binding and κ selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain [PDF]
, 1986 Elizabeth A. Young +5 more
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Characterization of big dynorphins from rat brain and spinal cord [PDF]
, 1987 Xie Gx, A Goldstein
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A dynorphin-like opioid in the central nervous system of an amphibian. [PDF]
, 1982 R I Cone, Alan Goldstein
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Individual differences in the neuropsychopathology of addiction. [PDF]
, 2017 Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
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Dynorphin-A alters the excitability of pyramidal neurons of the rat hippocampus
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The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation [PDF]
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