Frontiers in Cellular Neuroscience, 2016 The Neuropeptide S system, consisting of the 20-amino acid peptide neuropeptide S (NPS) and its G-protein coupled receptor (NPSR), modulates arousal, wakefulness, anxiety, and fear-extinction in mice.
Kay eJuengling +3 more
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Individual differences in the neuropsychopathology of addiction. [PDF]
, 2017 Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
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5-HT6R Viral Vector-Mediated Indirect Pathway Activation in the Dorsolateral Striatum: A Discussion on Basal Ganglia Habitual and Goal-Directed Circuits [PDF]
, 2018 Altering maladaptive behavioral tendencies is relevant for clinical interventions, making research on underlying mechanisms of habit essential. Mechanisms of habit are explored here with differential activation of the indirect pathway in the basal ...
Winn, Caleb S
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Neuroanatomy of the human hypothalamic kisspeptin system. [PDF]
, 2014 Hypothalamic kisspeptin (KP) neurons are key players in the neuronal network that regulates the onset of puberty and the pulsatile secretion of gonadotropin-releasing hormone (GnRH).
Hrabovszky, Erik
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Prenatal Testosterone Excess Decreases Neurokinin 3 Receptor Immunoreactivity within the Arcuate Nucleus KNDy Cell Population [PDF]
, 2015 Prenatal exposure of the female ovine foetus to excess testosterone leads to neuroendocrine disruptions in adulthood, as demonstrated by defects in responsiveness with respect to the ability of gonadal steroids to regulate gonadotrophin‐releasing hormone
Almeida +58 more
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Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice
Cell Reports, 2023 Summary: The mechanism by which arcuate nucleus kisspeptin (ARNKISS) neurons co-expressing glutamate, neurokinin B, and dynorphin intermittently synchronize their activity to generate pulsatile hormone secretion remains unknown.
Su Young Han +7 more
doaj
Arcuate nucleus homeostatic systems reflect blood leptin concentration but not feeding behaviour during scheduled feeding on a high-fat diet in mice [PDF]
, 2017 Acknowledgements T.B. was funded by a CASE studentship from the BBSRC and AstraZeneca. J.B. was a summer student from Bordeaux Sciences Agro and funded by student laboratory experience grant from the British Society of Neuroendocrinology. The authors are
Bake, T. +4 more
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TGF-β1 enhances cardiomyogenic differentiation of skeletal muscle-derived adult primitive cells [PDF]
, 2008 The optimal medium for cardiac differentiation of adult primitive cells remains to be established. We quantitatively compared the efficacy of IGF-1, dynorphin B, insulin, oxytocin, bFGF, and TGF-beta1 in inducing cardiomyogenic differentiation.
Abdel-Latif, Ahmed +9 more
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Involvement of dynorphin in anxiogenic effects of estrogen
BMC Pharmacology, 2009 Methods Dyn KO mice were generated by replacement of the entire coding region of the prodynorphin gene [2] and backcrossed onto C57bl/6N. Age and testing experiencematched female intact and ovariectomized (OVX) Dyn KO and wildtype (WT) mice at 3-8 months age were tested in all experiments.
Christoph Schwarzer +3 more
openaire +2 more sources
Perivascular expression and potent vasoconstrictor effect of dynorphin A in cerebral arteries.
PLoS ONE, 2012 BackgroundNumerous literary data indicate that dynorphin A (DYN-A) has a significant impact on cerebral circulation, especially under pathophysiological conditions, but its potential direct influence on the tone of cerebral vessels is obscure. The aim of
Éva Ruisanchez +6 more
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