Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]
, 2019 Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core +1 more source
Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior [PDF]
, 2017 Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the afferent circuitry that endogenously drives this neural activity and behavior, the downstream ...
Bhatti, Dionnet L. +6 more
core +3 more sources
Rising plasma nociceptin level during development of HCC: A case report [PDF]
, 2004 AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Folhoffer, Anikó +8 more
core +1 more source
Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]
, 2004 Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K. +4 more
core +1 more source
Perivascular expression and potent vasoconstrictor effect of dynorphin A in cerebral arteries.
PLoS ONE, 2012 BackgroundNumerous literary data indicate that dynorphin A (DYN-A) has a significant impact on cerebral circulation, especially under pathophysiological conditions, but its potential direct influence on the tone of cerebral vessels is obscure. The aim of
Éva Ruisanchez +6 more
doaj +1 more source
Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]
, 2016 It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A +64 more
core +1 more source
Exposure to chronic mild stress prevents kappa opioid-mediated reinstatement of cocaine and nicotine place preference [PDF]
, 2013 Stress increases the risk of drug abuse, causes relapse to drug seeking, and potentiates the rewarding properties of both nicotine and cocaine. Understanding the mechanisms by which stress regulates the rewarding properties of drugs of abuse provides ...
Al-Hasani, Ream +2 more
core +2 more sources
PLoS ONE, 2011 L-DOPA-induced dyskinesia is a troublesome complication of L-DOPA pharmacotherapy of Parkinson's disease and has been associated with disturbed brain opioid transmission.
Anna Ljungdahl +4 more
doaj +1 more source
Characterization of big dynorphins from rat brain and spinal cord [PDF]
, 1987 Xie Gx, A Goldstein
openalex +1 more source
Role of movement in long-term basal ganglia changes: implications for abnormal motor responses [PDF]
, 2013 Abnormal involuntary movements (AIMs) and dyskinesias elicited by drugs that stimulate dopamine receptors in the basal ganglia are a major issue in the management of Parkinson’s disease (PD).
FRAU, LUCIA +3 more
core +1 more source