Results 1 to 10 of about 495 (105)

Management of congenital dysfibrinogenemia in pregnancy: A challenging patient case

Research and Practice in Thrombosis and Haemostasis, 2021
Afibrinogenemia and congenital dysfibrinogenemia (CD) are rare conditions with limited information available for appropriate management. Previous case reports have demonstrated the safe and efficacious use of fibrinogen replacement therapy (FRT) as a ...
Megan Langer, Meredith Manire, Matthew Clarkson, Yazan Samhouri, Deep Shah, Rama Bhagavatula   +5 more
doaj   +2 more sources

Multidisciplinary team management of congenital dysfibrinogenemia in pregnancy: a case report [PDF]

BMC Pregnancy and Childbirth
Background Congenital dysfibrinogenemia is a rare autosomal dominant disorder involving abnormal fibrinogen function, leading to variable risks of bleeding and thrombosis.
Meng Jie He, Zhou Jun Wei, Fei Wang, Hai Ying Zhang   +3 more
doaj   +2 more sources

Spinal anesthesia in a patient with hereditary dysfibrinogenemia who underwent emergency cesarean delivery: a case report [PDF]

JA Clinical Reports
Background Dysfibrinogenemia causes abnormal fibrinogen production, leading to thrombotic or bleeding complications, which are relative contraindications for neuraxial anesthesia.
Sae Ono, Yuki Hosokawa, Mizue Kamiyama, Eriko Ohsugi, Michiko Gotanda, Yuka Yamashita, Rie Kato   +6 more
doaj   +2 more sources

Acquired dysfibrinogenemia caused by monoclonal production of immunoglobulin λ light chain [PDF]

Haematologica, 2007
Disorders of fibrinogen are usually caused by genetic mutations that result in low protein levels (hypofibrinogenemia) or an abnormal molecule (dysfibrinogenemia). However, environmental and plasma factors can have an acquired effect on its expression or
A. Dear, S.O. Brennan, M.J. Sheat, JM. Faed, P.M. George   +4 more
doaj   +2 more sources

“No End Point Detected”: A Unique Coagulation Profile Unmasking Dysfibrinogenemia

Case Reports in Hematology
Dysfibrinogenemia is a rare qualitative fibrinogen disorder that can present with bleeding, thrombosis, or both. We report a case of a young woman with first-trimester pregnancy loss and severe hemorrhage, whose coagulation tests reported “no end point ...
Kelsey Uminski, Xiu Yan Jiang
doaj   +2 more sources

Fibrin-bound thrombin determines clot structure and blood thrombogenicity in normofibrinogenemia and dysfibrinogenemia

Haematologica
In thrombosis and haemostasis, coagulation and platelet activation pathways culminate to form solid fibrin clots, which can become vaso-occlusive or prevent excessive bleeding.
Siyu Sun, Mark Roest, Rolf T. Urbanus, Elena Campello, Sarah Beck, Cristiana Bulato, Simon D. Connell, Philip G. de Groot, Timea Feller, Dana Huskens, Joke Konings, Rita Marchi, Harmen Middelveld, Patricia Oftering, Bernhard Nieswandt, Alessandro Casini, Robert A.S. Ariens, Paolo Simioni, Johan W.M. Heemskerk, Bas de Laat   +19 more
doaj   +2 more sources

Management and outcomes of women with low fibrinogen concentration during pregnancy or immediately postpartum: A UK national population‐based cohort study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Pregnant women with a fibrinogen level
Caroline Diguisto, Elfreda Baker, Simon Stanworth, Peter W. Collins, Rachel E. Collis, Marian Knight   +5 more
doaj   +2 more sources

PB2642: EVALUATION OF INNOVATIVE LABORATORY TESTS TO PREDICT A THROMBOTIC PHENOTYPE IN A FAMILY WITH DYSFIBRINOGENEMIA AND A NOVEL FGG MUTATION.

HemaSphere, 2023
Amaury Monard, Fs.C.J.I. Heubel-Moenen, Elisabetta Castoldi, Ilaria De Simone, P.E.J. van der Meijden, Kanin Wichapong, W.P.T.M. van Doorn, Stefano Spada, D.L.S. Hellenbrand, A.D.M. Stork, Hugo Ten Cate, E.A.M. Beckers, Y.M.C. Henskens   +12 more
doaj   +2 more sources

Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage

Asian Journal of Internal Medicine, 2023
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley, D. T. E. Wijegunaratne, S. Satheeshkumar, N. Ranasinghe   +3 more
doaj   +1 more source

Liver Transplantation in a Patient with Acquired Dysfibrinogenemia Who Presented with Subdural Hematoma: A Case Report

Turkish Journal of Hematology, 2017
Şencan Acar, Gökhan Güngör, Murat Dayangaç, Reyhan Diz Küçükkaya, Yaman Tokat, Murat Akyıldız   +5 more
doaj   +2 more sources