Results 111 to 120 of about 23,636 (243)

Dystrophin is phosphorylated by endogenous protein kinases [PDF]

open access: green, 1993
Monica De Luise   +8 more
openalex   +1 more source

Nestin Regulates Autophagy‐Dependent Ferroptosis Mediated Skeletal Muscle Atrophy by Ubiquitinating MAP 1LC3B

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Programmed cell death plays a critical role in skeletal muscle atrophy. Ferroptosis, an iron‐dependent form of programmed cell death driven by lipid peroxidation, has been implicated in various diseases, but its role in skeletal muscle atrophy remains unclear. Methods Ferroptosis in skeletal muscle atrophy was investigated using two
Shunshun Han   +8 more
wiley   +1 more source

Longitudinal Follow‐Up of Patients With Duchenne Muscular Dystrophy Using Quantitative 23Na and 1H MRI

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Quantitative muscle MRI commonly evaluates disease activity and muscle wasting in Duchenne muscular dystrophy (DMD). Disturbances in ion homeostasis contribute to DMD pathophysiology, but their relationships with disease progression is unclear. 23Na MRI may provide insights into the disease course and treatment response.
Teresa Gerhalter   +8 more
wiley   +1 more source

Myotubes from transgenic mdx mice expressing full-length dystrophin show normal calcium regulation. [PDF]

open access: green, 1994
W F Denetclaw   +4 more
openalex   +1 more source

Incidence of Radiologically Confirmed Fractures in Adults With Duchenne Muscular Dystrophy

open access: yesMuscle &Nerve, Volume 71, Issue 4, Page 558-563, April 2025.
ABSTRACT Introduction/Aims An increased risk of low trauma fractures is well documented in children and adolescents with duchenne muscular dystrophy (DMD). There is limited evidence regarding the fracture incidence of adults with DMD. The aim of this study was to examine radiologically confirmed fractures in adults with DMD and review bone health ...
Gavin Langlands   +3 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 7, Page 1416-1445, April 2025.
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis   +16 more
wiley   +1 more source

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